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Biomedical subjects

R Lindemann

Publications and source records attributed to R Lindemann.

At least 73 records · Page 4Linked to original sources
PubMed1987

Congenital neuronal ceroid lipofuscinosis. A case report.

A case of congenital neuronal ceroid lipofuscinosis, a 9-day-old male child of Pakistani parents, is reported. Only 5 congenital cases have been described previously. The cerebral and cerebellar cortex showed extensive nerve-cell loss. Granular material with histochemical characteristics of ceroid-lipofuscin was deposited in neurons, macrophages and glial cells throughout the brain. Similar material was found in macrophages in the lymphoid system and in certain other organs. Ultrastructurally, the material was identical with that described in the infantile type of ceroid lipofuscinosis. It is pointed out that the metabolic exchange between the blood of the mother and the foetus is not sufficient to prevent the intra-uterine progression of the disease.

Brain↗
PubMed1987

Neonatal retinal hemorrhages and neurobehavior related to tractive force in vacuum extraction.

Fifty clinically indicated vacuum extractions were studied to evaluate a possible relationship between neurobehavioral abnormality, retinal hemorrhages and the tractive force used for delivery. A Vacuum Extractor Recorder (Type SF 30, Knick), was used to measure the forces necessary for delivery of the head. Infants delivered by the use of extensive tractive force showed no greater incidence of neuropathology than those delivered with less tractive force. The retinal hemorrhages were equally distributed among the infants, irrespective of the tractive force applied or the neurobehavioral assessment. The implication is that retinal hemorrhages cannot be used to evaluate the extent of cerebral influence after birth and that the main cause of neurobehavioral abnormality is the condition leading to the use of the vacuum extractor (VE).

Adult↗
PubMed1984

Resuscitation of the newborn. Endotracheal administration of epinephrine.

During cardiopulmonary resuscitation, when an intravenous line is not present or easily obtainable, the intracardiac injection of drugs has been a traditional route of choice. However, the intracardiac administration may be associated with serious complications. We have given epinephrine endotracheally to ten newborn infants who all had bradycardia that did not respond to ventilation with 100% oxygen, to heart compression or to bicarbonate infusion. Epinephrine, 0.1 mg/ml was injected directly into the tracheal tube, and ventilation was immediately continued. A standardized procedure has been chosen by giving 0.25 ml to the infants weighing less than 1 500 g, 0.5 ml to those weighing between 1 500 and 2 500 g, and 1.0 ml to those greater than 2 500 g. All infants had a return to normal heart rhythm within seconds after installation of the epinephrine solution. The establishment of an intravenous line in small infants can be difficult, and the infants are usually intubated before the injection of epinephrine is considered. The endotracheal route should therefore be the first route of choice in the absence of a rapidly obtainable vascular access.

Asphyxia Neonatorum↗