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Biomedical subjects

R L Telander

Publications and source records attributed to R L Telander.

79 records · Page 5Linked to original sources
PubMed1977

Effect of proximal gastric vagotomy on gastric acid hypersecretion and hypergastrinemia after massive small bowel resection in dogs.

Fasting and postprandial gastric acid secretion and gastrin were determined in Heidenhain pouch dogs before (C) and after (R) massive enterectomy (five dogs) and after additional proximal gastric vagotomy (PGV) in three dogs. Basal acid output was unchanged (C = 7 +/- 2 microneq/hour; R = 11 +/- 4 microneq/hour), but postprandially the hourly (third through eighth hour) and cumulative acid outputs (C = 3.6 +/- 0.3 mEq/8 hour; R = 7.2 +/- 0.4 MEq/8 hour) were significantly increased by resection (P less than 0.001). Similarly, fasting gastrin was unaltered by resection (C = 41 +/- 2 pg/ml; R = 46 +/- 8 pg/ml), whereas hourly gastrin concentrations significantly (P less than 0.05) exceeded control values. Increased gastrin correlated linearly (P less than 0.02) with increased acid output. After PGV, basal acid levels remained unchanged (R = 4 +/- 2 micronEq/hour; PGV = 9 +/- 4 micronEq/hour), but postprandial acid output significantly exceeded prevagotomy values at all time periods (P less than 0.05). Cumulative acid output also was increased (R = 6.8 +/- 0.6 MEq/8 hour; PGV = 11.2 +/- 0.6 mEq/8 hour; P less than 0.001). Serum gastrin, however, remained unchanged. Hypersecretion of acid from Heidenhain pouches after massive enterectomy is increased further by PGV without a concomitant increase in serum gastrin.

Animals↗
PubMed1977

Lipoblastomatosis: a tumor of children.

A 10-month-old boy with circumscribed lobular lipoblastomatosis of the trunk was examined and treated at the Mayo Clinic. This is only the third case of lipoblastomatosis at our institution. The diagnosis depends on the pathologist, and the lesion must be differentiated from low-grade liposarcoma. Effective treatment involves adequate local excision and local reexcision for recurrence.

Child, Preschool↗
PubMed1976

Sequestration of the lung in children.

Nine cases of sequestration of the lung were seen in children. Bronchopulmonary sequestration of the lung is a distinct congenital anomaly and clinical entity that can be distinguished from other congenital abnormalities of the lung. Such a congenital anomaly must be considered in children who, on roentgenologic examination, are found to have an opacity in the lower lung fields. Intralobar bronchopulmonary sequestration often is associated with recurrent pulmonary sepsis, whereas extralobar sequestration is less likely to be symptomatic and usually exhibits no abnormal physical findings. In a unique case, we found an extralobar sequestration associated with an esophageal duplication that communicated with the sequestered lobe but not with the esophagus. This situation represents a transitional stage in embryonic development of extralobar sequestration. Intralobar and extralobar forms of sequestration show many common characteristics indicating a common embryogenesis. Surgical excision, consisting of lobectomy or segmentectomy, is safe and effective and may be accomplished without morbidity or mortality.

Age Factors↗
PubMed1976

Total parenteral nutrition in infants and children.

The current literature on pediatric parenteral alimentation, including some of its newer modifications, was reviewed. In light of this review, a 1-year experience with 20 patients on the pediatric surgical service of the Mayo Clinic who received total parenteral nutrition for a variety of life-threatening problems is reported. Our data confirm that premature infants, infants with intractable diarrhea, and both infants and adolescents with surgical problems precluding enteral feeding can be given sufficient parenteral kilocalories to regain lost weight and continue to grow, and that this can be done with a minimal rate of complications.

Diarrhea, Infantile↗
PubMedDate not supplied

The endorectal pull-through procedure in children and young adults: a follow-up study.

At our institution, proctocolectomy with rectal mucosectomy and ileoanal anastomosis with endorectal pull-through is now the procedure of choice for young patients with chronic ulcerative colitis and familial polyposis. We have followed up 66 patients (37 male and 29 female, with a median age of 16 years) for at least 6 months after closure of the temporary ileostomy. The patients were seen regularly in follow-up or were sent a comprehensive questionnaire to assess their condition. Twenty-two patients had the construction of a J-pouch, and 44 had a straight ileo-anal pull-through. Stool frequency, day (median 4 to 7 stools) and night (median 1 to 3 stools), was similar in the two groups. Voluntary continence was excellent in both groups during waking hours. Occasional night-time incontinence in small volumes, mild perianal itching, and minimal bleeding from irritation were similar in both groups. Most of the patients could distinguish gas from stool. When medication was used, bulk agents were usually chosen, with a nonspecific antidiarrheal agent taken occasionally. A few patients with the straight ileo-anal pull-through expressed some dissatisfaction early during the follow-up period; however, all but two patients expressed satisfaction later. Of the 66 patients, 41 had at least one complication during the postoperative period; however, in 26 the complications were minor. The more severe complications included small bowel obstruction (11 patients requiring surgical decompression), infection (one patient requiring surgery), and transient neuropathy (three patients).

Adenomatous Polyposis Coli↗