A randomized comparison of an immunosuppressive strategy using tacrolimus and cyclosporine in black heart transplant recipients.
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Black People↗
Biomedical subjects
R L Scott
Publications and source records attributed to R L Scott.
Racial differences in clinical outcome using tacrolimus and mycophenolate mofetil immunosuppression in heart transplantation.
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Black People↗
Effect of delayed refrigeration on plasma factors in whole blood collected in CPDA-2.
Extension of the time within which whole blood may be separated into components offers logistic advantages for the operation of remote mobile drawing teams. We evaluated the effect of an 8-hour hold of whole blood at room temperature before preparation of components. Plasma coagulation activity and opsonic factor content were studied in 14 units drawn into the anticoagulant-preservative solution citrate-phosphate-dextrose-adenine (CPDA-2). At the time of collection, an additional 7-ml aliquot was drawn into 1 ml of CPDA-2, the plasma separated and frozen immediately. Components were prepared from whole blood units allowed to rest undisturbed at 22 +/- 1 degrees C for 8 hours. After 8 hours, a significant decrement of about 10 percent was found in the concentration of fibrinogen, plasminogen, fibronectin, and activity of Factor V. Factor VIII activities (VIIIAHF and VIIIAGN) were not significantly different after 8 hours. Our results indicate that room temperature storage for 8 hours before component processing has minimal effects on potentially labile plasma protein factors using CPDA-2 anticoagulant-preservative solution.
Adenine↗
Difficult cases in heart failure. Novel diagnostic markers in heart failure: an emerging paradigm shift?
The differential diagnosis of dyspnea can be overwhelming in the presence of competing diseases. The recent advent of the peptide marker brain natriuretic peptide has ushered in an era of refined diagnostic capability in heart failure. We present a clinical scenario to illustrate the usefulness of this new biomarker assay in directing appropriate therapy for heart failure. (c)2001 CHF, Inc.
Journal Article↗
Postprandial glycemic response to orange juice and nondiet cola: is there a difference?
The purpose of this study was to compare the effects of unsweetened fruit juice and regular, decaffeinated soda on postprandial serum glucose levels in individuals with non-insulin-dependent diabetes mellitus (NIDDM) when these liquids are ingested separately as part of mixed meals. Eighteen individuals with NIDDM consumed three test breakfasts calculated using the diabetic exchange meal-planning system. Foods were identical in each of the breakfasts except for foods in the fruit exchange. Carbohydrate-equivalent amounts of fresh orange slices, unsweetened orange juice, and regular, decaffeinated Coke were consumed in breakfasts 1, 2, and 3, respectively. Serum glucose samples were drawn at fasting and 1, 2, and 3 hours postprandially. No difference was found in the postprandial serum glucose response when Coke versus orange juice was consumed in the breakfast. These findings question the appropriateness of using unsweetened fruit juices in routine meal planning for individuals with NIDDM.
Aged↗
Effects of hypocaloric dextrose and amino acids on body composition and nitrogen balance in rats.
Studies were conducted to compare the effects of isocaloric intake of glucose, amino acids, and combinations of these nutrients on nitrogen balance, body composition, and selected metabolic parameters of adult rats. Diets were administered either orally or intravenously at 20% (semi-starvation) of the daily caloric requirement. Although nitrogen balance was improved when all calories were supplied as amino acids when compared to glucose alone, one-half the amino acids could be replaced with glucose without sacrificing nitrogen balance. Animals from the semi-starvation treatment showed similar weight and body composition changes, there was no apparent difference whether the diets were administered orally or intravenously. These results indicate that replacement of at least one-half the calories of an all amino acid hypocaloric diet with glucose does not adversely affect body composition weight change or nitrogen balance, but may reduce blood urea nitrogen, ketosis, and cost of nutritional support.
Amino Acids↗
An interview with Rick Scott. Interview by Connie R Curran.
Richard (Rick) L. Scott is president and chief executive officer of Columbia/HCA Healthcare Corporation, the nation's largest health care services provider. In this interview, he discusses principles of patient care, measuring and sharing systems, the future of academic health centers, and the importance of information dissemination.
Chief Executive Officers, Hospital↗