Search PubMed⌕ Search

Biomedical subjects

R L Price

Publications and source records attributed to R L Price.

At least 55 records · Page 3Linked to original sources
PubMed1983

Spontaneously regressing retinoblastomas, retinoma, or retinoblastoma group 0.

A 5-year-old boy had a gray, translucent retinal mass containing calcified nodules and surrounded by retinal pigment clumping and atrophy. The eye was enucleated and the patient has remained well for seven years. Microscopic examination disclosed an intraretinal tumor composed of benign-appearing cells in a bed of well-vascularized ground substance with calcific foci. There was surrounding retinal pigment epithelial hyperplasia but no peripheral necrosis or signs of tumor regression. There were no mitoses, cellular pleomorphism, nuclear atypia, rosettes, or other characteristics of malignancy. Tumors with this typical fundus appearance have been termed spontaneously regressing retinoblastoma or retinoma. Although the tumor in this patient was histopathologically benign, it carries the same genetic risk as a retinoblastoma. A better term for this lesion, therefore, is retinoblastoma group 0.

Child, Preschool↗
PubMed1982

Interocular transfer of the motion aftereffect in strabismus.

The interocular transfer of the motion aftereffect (MAE) was measured in three groups of strabismic subjects (six with monofixation, nine with alternation, four with anomalous retinal correspondence) and compared with a group of four normal subjects. The duration of the MAE was measured using sinusoidal gratings of 0.5 c/deg subtending a visual angle of 8. Contrary to previous findings, a substantial amount of MAE transfer was found in some stereoblind individuals with strabismus. The mean amount of transfer for each group was found to correlate with binocularity; the order of decreasing transfer being: normal, monofixation, alternation, and anomalous retinal correspondence (ARC). This reduction in transfer which accompanied the loss of binocularity was asymmetric, that is, right-left transfer did not equal left-right transfer. The amount of asymmetry was found to correlate inversely with the amount of transfer. The direction in which the greatest transfer occurred did not correlate with visual acuity. These data substantiate the overall poor binocularity in subjects with ARC, and the relatively good binocularity of subjects with monofixation. Furthermore, the substantial amount of transfer found in subjects with alternating strabismus may be a measure of potentially achievable binocularity.

Adolescent↗
PubMed1982

Toxicity of aflatoxin B1 to penaeid shrimp.

Single intramuscular injections of aflatoxin B1 into the tail muscle of Penaeus stylirostris produced 24- and 96-h median lethal doses of 100.5 (78.3 to 129.0) and 49.5 (29.8 to 82.3) mg/kg, respectively. A toxicity curve showed no threshold at the levels tested. The mortality response in a feeding study with P. vannamei was not dose dependent, but tissue and organ damage were similar to that seen in injected animals.

Administration, Oral↗
PubMed1982

Scleral grafting in the management of ligneous conjunctivitis.

Ligneous conjunctivitis is a rare, usually bilateral, chronic membranous conjunctivitis, which begins acutely in childhood and persists for many years. In view of the poor results obtained with other forms of therapy in the past, the resection of the involved conjunctiva and tarsus with the grafting of donor sclera is offered as another alternative in the management of this distressing condition.

Adult↗
PubMed1981

Contact lenses in the management of myopic anisometropic amblyopia.

We treated 16 patients aged 1 1/2 to 11 years with myopic anisometropic amblyopia with contact-lens correction of refractive error and occlusion. The degree of visual improvement compared favourably with that reported with the use of spectacles. There were no complications from contact lenses, and only one patient required anesthesia for fitting. Contact lenses appear to be more satisfactory than spectacle lenses in the management of myopic anisometropic amblyopia in regard to cosmesis, comfort, and treatment compliance. Patients with myelinated retinal nerve fibers and unilateral severe myopia had a poor visual prognosis. Treatment should not be abandoned in these children, but prolonged occlusion is not indicated. The presence of strabismus at the start of treatment appeared to have little effect on the final visual results. Most patients with strabismus responded well to occlusion, and all such children should be considered candidates for treatment of their amblyopia.

Amblyopia↗
PubMed1981

Citrus artifact interference in aflatoxin M1 determination in milk.

Dried citrus waste was fed to dairy cows, their milk was extracted, and aflatoxin M1 was quantitated by using both high pressure liquid chromatography (HPLC) and thin layer chromatography (TLC). Results indicate that a compound from the citrus waste, which is excreted into the milk, interferes with the HPLC determination of aflatoxin M1 in milk and causes a false positive test. This interference can be overcome by using TLC with proper selection of developing solvents.

Aflatoxin M1↗
PubMed1980

Myxobolus microcystus sp. N. (Protozoa: Myxosporida) from the gills of Micropterus salmoides (Lacépède 1802) in southern Illinois.

Myxobolus microcystus sp. n. is described from the gills of the largemouth bass, Micropterus salmoides. Mean spore dimensions (in micrometers) are as follows: spore length 12.5; spore width 7.5; spore thickness 5.5; polar capsule length 6.5; polar capsule width 2.5; extended length of polar filaments 21 to 37; polar filaments with 6 to 7 coils. In histological sections, hyperplasia of infected filaments, atrophy of lamellae, partial occlusion of the efferent artery, and reduction in the number of peripheral goblet cells were observed.

Animals↗
PubMed1979

Silicone intubation of the lacrimal system: loop retraction as a complication.

Inadvertent retraction of silicone tubing after nasolacrimal intubation occurs with some frequency. This problem may be managed in sequential fashion with probing, dacryocystostomy or dacryocystorhinostomy depending on the needs of the patient at the time of occurrence and the original rationale for utilization of the technique.

Aged↗
PubMed1978

Normal urinary excretion of catecholamine catabolites in children with retinoblastoma.

Urinary catecholamine catabolites, homovanillic acid, vanillylmandelic acid, total metanephrines, and total catecholamines were assayed in 12 patients with newly diagnosed retinoblastoma prior to surgery and treatment. These values were within normal limits for the ages of all 12 patients, including one with metastases to brain, liver, lymph nodes, and bone marrow. The predictive value and efficiency of these tests in the diagnosis of retinoblastoma are insufficient to warrant their continued use on a routine basis.

Catecholamines↗
PubMed1976

Role of Tenon's capsule in postoperative restrictions.

Management of all restricted strabismus cases is difficult and frequently will require two or more procedures. The prevention of these restrictions at the time of primary surgery is far more important. All tissue should be handled as gently as possible, with smooth or fine-tip forceps, avoiding large fixation devices. Sharp dissection is essential - tissue should not be torn but cut carefully and sharply with scissors under direct visualization. The conjunctival and Tenon's capsule incisions should not be made directly over the muscle; this will result in scarring of the muscle to Tenon's capsule or of Tenon's capsule to the muscle insertion stump, promoting restriction. The muscle should be isolated under direct visualization or inspected carefully after isolation, with great care taken not to incorporate any unnecessary Tenon's capsule in the muscle and to avoid the inferior oblique msucle on lateral rectus muscle surgery. A blind, deep sweep is completely contraindicated. The intermuscular membranes, check ligaments, and muscle foot plates must be completely severed, under direct visualization, well beyond the resection site in the course of a resection,and 5 to 8 mm. behind the insertion in the course of a recession. Complete hemostasis during the procedure and at its completion is essential; 2.5 percent phenylephrine and minimal cautery will help achieve this. Since cautery will result in a scar of Tenon's capsule to that area of the sclera, it should be used as little as possible. Phenylephrine 2.5 percent has been used safely with halothane anesthesia in many patients without significant arrhythmias. The secondary treatment of restriction is very difficult, whereas their prevention requires only good surgical technique and careful attention to detail.

Adult↗