Profile of T and B lymphocytes of peripheral blood and lymphoid organs of protein deficient guineapigs.
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Biomedical subjects
Publications and source records attributed to R Kumar.
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Until recently there were no reports regarding the presence of xanthine oxidase (xanthine:oxygen oxidoreductase, EC 1.2.3.2) in plants. Direct evidence for its presence in lentil seedlings is reported here. Xanthine oxidase activity increases with the period of germination, reaching a maximum at 24 h and decreasing thereafter. The pH optimum for its activity is at pH 8.0. Almost equal activity is observed against xanthine and hypoxanthine. The Km for xanthine is 1.05 mM, and considerable inhibition is observed at high substrate concentration.
The coagulopathy induced by vitamin K deficiency commonly results from our lack of awareness of the clinical setting associated with vitamin K deficiency. Thirteen cases are reviewed to illustrate the clinical correlates most frequently observed. Dietary deficiency was always present, but concomitant antibiotic therapy was not an absolute requirement. The postoperative patient is at high risk, as is the patient with cancer or renal failure. Abnormal bleeding was common, but significant hemorrhage occurred only in postoperative patients. Factor assays were helpful and occasionally necessary to make the diagnosis, but a therapeutic trial with parenteral vitamin K was often enough to provide the right diagnosis. Greater awareness of this deficiency syndrome is necessary to avoid the serious morbidity that often results.