[New synthesis and 14 C-labelling of bilirubin-IXalpha].
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Biomedical subjects
Publications and source records attributed to R Kohler.
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Comparison of solid-phase radioimmunoassay (S-PRIA) and agar-gel diffusion for detecting antibodies to candida organisms was undertaken in patients with systemic candidiasis, candida colonization, noncandida febrile illnesses, and in healthy controls. Radioimmunoassay results were highly reproducible when the same sera were tested on three different days. Sera from all three groups of patients had higher counts per minute (CPM) by S-PRIA then sera from control subjects. Although positive precipitins and high CPM occurred frequently in patients with systemic candidiasis, both precipitins and high CPM were detected in some sera from patients with colonization without system disease.
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The authors have used Dwyer's procedure in 50 patients with a maximum follow-up of 4 years. The average correction was 76 per cent--that is the average curve was 73 degrees before operation and 16 degrees after operation. The upper compensatory curve was also corrected from an average of 45 degrees to an average of 28 degreees. Associated kyphosis was corrected by 75 per cent in association with correction of rotation. In the follow-up, a loss of 7 degrees of correction in the main curve was noted. It was related to rupture of the cable (5 cases), to a high rate of non-union (50 per cent) and to too short a length of fixation. When curves were correctly fixed, loss of correction was only of 2 to 3 degrees. The main advantage of the Dwyer procedure is to allow limited fusion with horizontal levelling of unfused intervertebral spaces.
Pelvic obliquity due to spinal deformity is a well defined syndrome. Its natural history is related to the evolution of the scoliosis. The authors describe two types of pelvic obliquity--total pelvic obliquity in which the sacrum is the lowest vertebra of the lumbar curve and subtotal pelvic obliquity in which there is some compensation between L5 and the sacrum. Seventeen patients were operated on. The Dwyer's procedure was found to be satisfactory in total pelvic obliquities from the point of view of correction and stabilization. In subtotal pelvic obliquity, an additional lumbosacral fusion by a posterior approach was found to be necessary.
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Obstetrical fracture has not a bad character, because of quick healing and, above all, because of extraordinary modelling by growth. The authors record 33 fractures of long bones which confirm this good prognosis. 20 birth fractures of the clavicule associated with brachial plexus palsies are recorded on account of their pathogenic, diagnostic and therapeutic intricacies. Prognosis of obstetrical traumatic separation of the epiphysis (epiphysiolysis) would be more preoccupying. This feeling is not given off the series of 28 observations recorded which conern 13 upper humeral, 6 lower humeral epiphysis, 1 of 6 upper femoral and 1 lower femoral epiphysis, of upper and lower of tibia. Diagnosis is not so easy, helped, if necessary, by arthrography. The clinical aspect of "pseudo-dislocation" associated with periostal callus, early appearing (about on the 10th day) rectifies diagnosis. Early treatment, as little aggressive as possible, (essentially orthopedic management by tractions along the axis of limb, giving up an anatomy as close as possible to normality) avoids sequellae, not existing at shoulder nor elbow and, if they exist, extremely decreased at hip, and the surgical management of which is always delayed. Initially good result of one birth dislocation of cervical spine, precedently recorded is considerably impaired.