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Biomedical subjects

R Kessler

Publications and source records attributed to R Kessler.

At least 217 records · Page 12Linked to original sources
PubMed1979

Intraperitoneal rupture of pseudodiverticulum of bladder.

A case is presented of a pseudodiverticulum of the bladder which developed after a bladder rupture nine years previously. In this case, rupture of the pseudodiverticulum occurred intraperitoneally. The pseudodiverticulum communicated with the bladder via a small fish-mouthed opening surrounded by attenuated fibrotic bladder wall.

Adult↗
PubMed1979

Transplacental exposure to diethylstilbestrol in men.

Diethylstilbestrol (DES) was widely prescribed during the late 1940s and early 1950s for complications of pregnancy. Twenty-four men exposed to DES in utero were examined and compared with twenty-four age-matched controls; contrary to previous reports, we found no difference between the two groups in their psychosexual history, medical history, genital examination, or semen analysis.

Adult↗
PubMed1978

Vaginal cystectomy.

The technique of vaginal cystectomy is described in 2 patients. These patients were particularly suited for vaginal cystectomy because severe lower abdominal scarring from previous multiple abdominal operations would have made the standard suprapubic approach difficult.

Adult↗
PubMed1977

Depressive mood and adolescent illicit drug use: a longitudinal analysis.

Through the technique of Goodman's log linear method, longitudinal data are analyzed to clarify the relationship between depressive mood and illicit drug use among youths. A representative sample of adolescents (N = 8206) from New York State secondary schools was followed over one academic year. At one point in time, users of illicit drugs other than marihuana (multiple drug users) were significantly more depressed than either nonusers or users of marihuana only. Differing interactive relationships were found over time depending upon the drugs involved. Depressive mood was related to the onset of marihuana use among nonusers and to the termination of marihuana use among users. Depressive mood also predicted the use of other illicit drugs by marihuana users. While the beginning use of illicit drugs other than marihuana was positively associated with increased depressive mood, continued multiple drug use was related to reduced depressive mood.

Adolescent↗
PubMed1976

Renal arteriovenous fistulas.

A review of the literature reveals that aggressive treatment of symptomatic intrarenal arteriovenous fistulas, whether by surgical or radiologic techniques, is generally indicated. The exception is those fistulas which result from closed renal biopsy since these usually heal spontaneously. The ultimate goal of any form of therapy is the maximal preservation of renal tissue. Methods of treatment are discussed, and a review of classification, etiology, incidence, symptoms, physiologic consequences, and means of diagnosis is given. A case of post-traumatic intrarenal arteriovenous fistula with ipsilaterally elevated renal vein renin and hypertension, cured by partial nephrectomy, is presented.

Adult↗
PubMed1975

Paired moving charge model of energy coupling. III. Intrinsic ionophores in energy coupling systems.

The experimental basis for the postulated role of intrinsic ionophores in mitochondrial ion transport and energy coupling is summarized. Intrinsic ionophores appear to be linked to, or contained within, specific ionophoroproteins localized in the inner membrane, and the isolation of these ionophores requires their release from the ionophoroproteins. At least ten different species of ionophores have been isolated from the mitochondrion, five of which have been wholly or in part chemically identified. Intrinsic ionophores have been implicated in the activation of inorganic phosphate in ATP synthesis and hydrolysis, and in the contol of the coupling modes. The presence of ionophores in soluble proteins such as troponin and in ATP-energized kinases has been demonstrated.

Biological Transport, Active↗
PubMed1969

Albumin to ascites: demonstration of a direct pathway bypassing the systemic circulation.

The transport of plasma albumin and newly made albumin into ascitic fluid was studied in eight patients with cirrhosis and ascites. The thoracic duct was cannulated in two patients and lymph collected over a period of 2 hr. Simultaneously albumin-(131)I and carbonate-(14)C were injected intravenously. The albumin-(131)I measured the transfer of plasma albumin into ascites and into thoracic duct lymph. The carbonate-(14)C, by labeling newly formed albumin, permitted the estimation of the transfer of newly formed albumin into plasma, ascites, and lymph. If the newly synthesized albumin entering ascites and thoracic duct lymph is delivered initially into the plasma, then the ratios of the albumin-(14)C and -(131)I in ascites and lymph compared with the content of albumin-(14)C and -(131)I in plasma would be identical. However, if some newly formed albumin is delivered directly into ascites or lymph, the ratio for albumin-(14)C would be higher than that for albumin-(131)I in lymph or ascites. The ratios of both labeled albumins found in ascites or lymph are expressed as per cent of the total plasma pool. In the eight patients studied 4.2-11.7% of the albumin-(14)C in plasma was found in ascites in 2 hr whereas only 0.4-2.2% of plasma albumin-(131)I entered in this same period. In the two patients studied during thoracic duct lymph drainage 6.1 and 13.5% of newly made albumin-(14)C appeared in lymph in 2 hr whereas only 2.8 and 3.8% of plasma albumin-(131)I was found in the lymph. In cirrhosis with ascites some newly formed albumin entered ascites and thoracic duct lymph by a direct pathway from the liver bypassing the systemic circulation.

Albumins↗