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Biomedical subjects

R K Garg

Publications and source records attributed to R K Garg.

152 records · Page 9Linked to original sources

Volvulus of the small intestine.

A series of seventy-five cases of volvulus of the small intestine are reviewed. There is a 14.2% incidence of this condition among cases of acute intestinal obstruction. It is more common than cecal volvulus but less common than sigmoid volvulus. The patients are usually healthy, poor, adult villagers whose diet is heavy and vegetarian with a high roughage content; they mainly do hard manual work. It is difficult to make a correct preoperative diagnosis. In this series, the percentage of primary volvulus is 73.33% and of secondary is 26.66%. The etiology, incidence, symptomatology and mortality are studied.

Adolescent↗

Demonstration of sugar and determination of the secretor status from urine stains of diabetics.

In this preliminary study urine an saliva samples have been typed for the presence of ABH-Blood-Group specific substances from fresh samples and the stains prepared therefrom. Fresh samples have been typed by the Absorption-Inhibition and the stains by the Absorption-Elution-Technique. 42 of saliva and 37 of the urine samples (fresh) have been found to be secretors, while from the stains 36 (= 72 Prozent) and 32 (= 64 Prozent) samples would be typed correctly from saliva and urine stains. The Benedict's Test for sugar has been found to be positive in 35 of the fresh urine samples where as from stains 31 (= 62 Prozent) could be typed correctly. On the basis of the above study the following conclusions emerge out. 1. Benedict's Test for sugar may be conveniently used in the field of Forensic Science for analysing urine stains in order to exclude persons not actually involved in a crime. 2. Persons who secret ABH-Substances in saliva may not in all cases secrete them in urine.

ABO Blood-Group System↗

Drug treatment of neurocysticercosis.

Neurocysticercosis, the most common parasitic disease of the central nervous system, was treated surgically for a long time. Praziquantel (an isoquinolone) and albendazole (an imidazole) are anticysticercal drugs that are currently being used for the treatment of neurocysticercosis. Both have been reported to eliminate or markedly reduce the number and size of cysticerci. Albendazole is less expensive than praziquantel, and is as effective when given for 8 days as compared to longer periods. In a small number of comparative trials, albendazole appeared to be slightly more effective than praziquantel for the treatment of parenchymal cysticercosis. Albendazole has also been found effective in ventricular, subarachnoidal and racemose forms of the disease. However, the response to treatment is not universal. Treatment with these drugs has been associated with a high frequency of adverse reactions, probably due to the host's inflammatory reaction to the dying parasites. Headache, nausea and seizures are common but usually transient. Steroids appear to ameliorate these effects and their concomitant administration has been advocated. However, no data are available to support this view. The rationale of medical therapy in spinal cysticercosis is presently based on the reported efficacy of anticysticercal drugs in cerebral cysticercosis. A marked improvement in an associated seizure disorder following anticysticercal therapy has been observed. Though seizure control is better, the total duration of anti-epileptic drug therapy has not been determined. Some single enhancing computed tomography lesions in patients of epilepsy may be benign forms of neurocysticercosis. The spontaneous resolution of a majority of these lesions has led to doubts of them being merely infective in aetiology. Also, a controlled trial could not demonstrate any beneficial effect of albendazole on such lesions. Hence, most authors recommend that these patients should be treated with anti-epileptic drugs only. Doubts persist about the efficacy of anticysticercal drugs in altering the natural course of the disease and the reported tendency of cysticercus lesions to resolve.

Adrenal Cortex Hormones↗