[Immunoglobulins, interferon and T- and B lymphocytes in patients with bronchial asthma vaccinated with Alavac, Vibrio cholerae vaccine and polyvaccine].
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to R Jankowska.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Recent findings in animals indicate the influence of beta-endorphins on bronchial smooth muscle tone. The purpose of our study was to compare beta-endorphin concentrations in sera of asthmatics during the asymptomatic period and after histamine provocation. The study was performed in a group of 32 asthmatic patients and 12 healthy subjects. Beta-endorphin concentrations were evaluated by radioimmunoassay (J-125 beta-Endorphin Human) twice daily at 8 a.m. and 10 a.m., and also before and after histamine provocation. No significant differences were found in endorphin concentrations for both normal controls and asthmatics at 8 a.m. and 10 a.m. We demonstrated a statistically significant increase in endorphin concentrations in asthmatics as compared to the controls. We found a statistically significant decrease of beta-endorphin concentrations after histamine provocation in the asthmatic group.