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Biomedical subjects

R J Coskey

Publications and source records attributed to R J Coskey.

At least 55 records · Page 3Linked to original sources

An unusual organoid nevus.

The sites of predilection, stages of development, and suggested therapy for organoid nevi are discussed herein, and the case of an unusual nevus is presented.

Adolescent↗

Contact dermatitis due to multiple corticosteroid creams.

A patient was allergic to the corticosteroids halcinonide, fluocinonide, desonide, and triamcinolone acetonide. She also was allergic to ethylendiamine hydrochloride, neomycin, thimerosal, formaldehyde solution, and nystatin.

Adolescent↗

Papular mucinosis.

Most patients previously reported to have papular mucinosis had the generalized lichenoid papular form (scleromyxedema) with abnormal gamma globulin. Microscopic examination of affected skin showed increased acid mucopolysaccharides in the dermis and proliferation of fibroblasts. Our patient had the discrete form of papular mucinosis without abnormal serum gamma globulin but with increased amounts of acid mucopolysaccharides in the dermis and no proliferation of fibroblasts.

Adult↗

Eruptions due to oral contraceptives.

Three patients developed eruptions attributable to oral contraceptives. The eruptions of two of the patients resolved when the women discontinued the use of oral contraceptives. The third patient changed the type of oral contraceptive she was taking, and the eruption subsequently subsided.

Adult↗

Trichodiscoma.

Explore the source record for details and available documents.

Female↗

Acne: treatment with minocycline.

Forty-seven patients with acne, unresponsive to tetracycline and erythromycin, were treated with 100 mg minocycline daily. About one-quarter showed a 50% improvement or better. Five patients became dizzy during the first week of therapy, making it necessary to stop the medication in four instances. Two patients stopped treatment after several months because of esophagitis in one and headaches in another. Vestibular side effects are the most common complication of treatment. Patients should be warned about this side effect and if it occurs should avoid driving or handling machines. In some instances, dizziness may be so severe that the drug will have to be discontinued.

Acne Vulgaris↗

Bowen disease associated with porokeratosis of Mibelli.

A 73-year-old woman developed Bowen precancerous dermatosis in an area of porokeratosis of Mibelli on her leg. This is the fourth reported case of Bowen disease arising from porokeratosis of Mibelli. The recent literature indicates that porokeratosis of Mibelli may be due to an abnormal clone of cells, predisposing affected individuals to development of malignant neoplasms over the involved areas.

Aged↗