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Biomedical subjects

R J Coskey

Publications and source records attributed to R J Coskey.

At least 19 recordsLinked to original sources
PubMed1992

Current dermatologic therapy.

This article reviews therapeutic advances reported in the English-language literature during 1991. Readers should review the original article in full before attempting any experimental or controversial therapy.

Humans↗
PubMed1991

Dermatologic therapy: 1990.

This article reviews significant therapeutic advances that have been reported in the English-language literature during 1990. Readers should review the original article in full before attempting any new experimental or controversial therapy.

Clinical Trials as Topic↗
PubMed1990

Dermatologic therapy: December 1987 to December 1988.

In this article I have reviewed the significant therapeutic advances that have been reported in the English-language literature from December 1987 to December 1988. Clinicians should read the original articles in toto before attempting any new experimental or controversial therapy.

Acne Vulgaris↗
PubMed1989

Letterer-Siwe disease in adults.

Histiocytosis X (HX) is a rare disorder of histiocytic proliferation characterized by a broad spectrum of clinicopathologic disease. An unusual case of Letterer-Siwe disease (LSD) or subacute disseminated HX in a 71-year-old woman is presented. The patient had a 3-year history of splenomegaly before skin lesions developed. She presented to our clinic at 1.5 years later and the diagnosis of HX was made by skin biopsy. Topical nitrogen mustard (NM) therapy resulted in complete clearing of cutaneous lesions. Her condition was stable over the next 10 months. However, she subsequently suffered a rapid and fatal dissemination of her disease. Systemic treatment with prednisone, vinblastine sulphate, and suppressin A (SA) (a calf thymus derived hormone preparation that specifically induces suppressor T-cells) was ineffective. Characteristic histopathologic, immunohistochemical, and electron microscopic findings of HX are illustrated. A review of the adult cases of LSD and treatment options for HX are presented and discussed.

Aged↗
PubMed1988

Dermatologic therapy: December 1986 to December 1987.

In this article I review significant therapeutic advances reported in the English literature from December 1986 to December 1987. Readers should review the original articles in toto before attempting any new experimental or controversial therapy summarized.

Dermatologic Agents↗
PubMed1987

Dermatologic therapy: December 1985 to December 1986.

I have reviewed the significant therapeutic changes reported in the English literature between December 1985 and December 1986. Readers should review the original articles in toto before attempting any new experimental or controversial therapy summarized.

Clinical Trials as Topic↗
PubMed1987

Diagnosis and treatment of impetigo.

Sixty patients with impetigo were seen in a private practice. Cultures of specimens from all but one patient grew coagulase-positive Staphylococcus aureus. The culture of one patient grew pure group A beta-hemolytic streptococcus. The cultures of six patients were mixed, having streptococci and S. aureus. In all but one instance the staphylococci were resistant to penicillin and ampicillin. We recommend that all centers treating patients with superficial skin infections have a method of screening or spot checking their patient population to determine antibiotic sensitivities and the frequency and distribution of these infections. Then, if bacteriologic and antibiotic sensitivity studies mandate, a switch in antibiotics should be contemplated.

Administration, Oral↗
PubMed1987

The association of basal cell carcinomas with other tumors.

We report the case of a patient who had a lesion on the back that clinically resembled a basal cell carcinoma, but histologically showed changes of a basal cell carcinoma and a nodular malignant melanoma. We also review the literature on the association of basal cell carcinomas with other tumors.

Back↗
PubMed1986

Diagnosis and treatment of chalazia.

A patient with recurrent chalazia is described. This patient also had acne rosacea. The clinical and histologic characteristics of chalazia are described. In addition, therapy for chalazia is presented, with emphasis being given to conservative therapy.

Cysts↗
PubMed1979

Recurring digital fibrous tumor of childhood.

Two cases of recurring digital fibrous tumor of childhood are reported. Both patients were infants who had lesions on the toes or fingers. In one case the lesions recurred after surgical excision and in the other the lesions started to resolve without therapy. The histologic sections of tissue showed the intracytoplasmic inclusion bodies typical of this condition.

Female↗
PubMed1979

Facial granuloma annulare.

Of six cases of granuloma annulare of the face, three cases were not associated with lesions on the extremities or trunk. Histologic examination exhibited typical features of granuloma annulare. One patient's lesion was a recurrent solitary subcutaneous nodule.

Adolescent↗