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Biomedical subjects

R Ionescu

Publications and source records attributed to R Ionescu.

At least 55 records · Page 3Linked to original sources
PubMedDate not supplied

Predictors of outcome in depression.

Several socio-demographic, family and clinical history variables, stressful life events, index episode characteristics, symptom severity, clinically and psychometrically assessed personality type and traits, and treatment were evaluated as potential predictors of multiple outcome criteria in a sample of 157 outpatients and inpatients meeting commonly used criteria for depression episodes. Outcome criteria included: severity scores on the final evaluation, improvement rate, impairment level of functioning, clinically rated treatment response, episode duration and relapse frequency in one year follow-up. Gender, personality structure and type, stressful life event characteristics, prior episode number, clinical status after the last episode, symptom length at intake, initial symptom severity, psychotic and endogenous features emerged as significant predictors of depression outcome in univariate analyses. The combination of independent variables by multivariate regression analyses improved outcome prediction.

Adolescent↗
PubMedDate not supplied

Cognitive and motor retardation in depression.

The study analysed the profile of psychomotor retardation in depression by clinically and psychometrically assessing its motor, speech and cognitive components. Psychomotor performance level of a group of 100 moderately depressed patients was significantly lower than that of controls on most psychometric tests. The interrelations among the variables evaluating various aspects of the depressive psychomotor retardation were examined and factor analyses were performed. Clinical ratings of motor, speech and mental retardation were strongly intercorrelated and a general factor emerged. When psychometric evaluations of depressive psychomotor retardation were factor analysed only separate factors characterizing cognitive and motor slowing were identified. Few and weak correlations were recorded between clinical and psychometric evaluations of depressive psychomotor retardation. Factors responsible for psychomotor slowing in depression were discussed.

Adult↗