Biomedical subjects
Publications and source records attributed to R Inglis.
Complications of recently used coding systems, error sensitivity and limited reliability of results of data in daily use still do not match with the benefit of data processing in trauma surgery. The relevant advantages of an optical mark reader based data processing system are presented.
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Results are presented after operative treatment of 195 patients with extracapsular proximal femoral-bone-fractures. After accident early operation time is requested. Operation risk being small, this treatment is regarded as treatment of first choice.
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Explore the source record for details and available documents.
Explore the source record for details and available documents.
Review of the operations of 20 Washington, DC, area hospitals' emergency departments raised some important questions about the care of the emergency patient. This article answers some of those questions and outlines methods for improving the operations of the emergency department.
Development of the hybridoma technique has made the identification of several new tumor antigens possible. Although it was hoped that they would be more tumor-specific, none of these markers are found exclusively in tumor or in serum of tumor patients. Compared with carcinoembryionic antigen (CEA) and liver function tests, the roles of these markers (CA 19-9, CA 125, CA 15-3) were prospectively evaluated in 115 patients with colorectal liver metastases. Patients were classified according to tumor volume (T1 less than 25%, T2 25-75%, T3 greater than 75%), and the extension of infiltration (solitary/multiple/diffuse; unilateral, bilateral). Patients with benign liver or biliary disease served as a control group (n = 63). Overall sensitivity was 87% for *1, 50% for *2 and 38% for *3, with a significant correlation with tumor size. CEA serum levels were elevated in 88% of all patients. CA 19-9 was less sensitive: positive in 59%. Because of some complementary elevations, the combined use of CEA, CA 19-9 and CA 125 raised sensitivity to 94%. CA 19-9 and LDH could be useful for confirmation because of their higher specificity; however, the specificity of CEA rose to 93% on using a cut-off of 10 ng/ml instead of 3 ng/ml. The results indicate that CEA and CA 19-9 as well as liver function tests are helpful for preoperative staging in conjunction with imaging procedures before liver resection or regional chemotherapy.