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Biomedical subjects

R Hauser

Publications and source records attributed to R Hauser.

At least 145 records · Page 8Linked to original sources

Financial reserve. Hospitals leery of credit lines, factoring receivables.

Opening lines of credit and factoring (selling) accounts receivable are two ways to generate operating cash that non-healthcare industries have long used successfully. A recent survey of hospital officials across the nation, however, showed these techniques are used infrequently in health care. Among the 281 hospitals responding: Only 45 percent use lines of credit; Less than 5 percent pursue accounts receivable factoring; and Only 12 percent plan to begin factoring receivables in the future. As hospitals look for ways to offset depleted cash reserves, these percentages may increase.

Accounts Payable and Receivable↗

Wife or Frau, women do worse: a comparison of men and women in the United States and Germany after marital dissolution.

Longitudinal data from the Panel Study of Income Dynamics and the German Socio-Economic Panel show that in the Federal Republic of Germany, women experience even sharper drops in economic status immediately after a marital split than in the United States, while German and American men fare about the same. German social policy does little to reduce the disparities.

Divorce↗

[A1 and A2 blood group substances: are there structural differences?].

Blood group substances were extracted from erythrocytes of blood groups A1 and A2 and separated using HPTLC. Identification of blood group A was carried out on the chromatogramm using the PAP-technique. The specific demonstration of the serologically active glycosphingolipids allowed a comparison of the A1 and A2 blood group substance bands. The difference between the A1 and A2 Substances appears to be only a quantitative one.

ABO Blood-Group System↗

[Explanation of nonspecific serologic reactions in decomposed bone tissue].

Bone fragments were stored in water for 2 years at room temperature and investigated serologically using the following methods: Absorption-elution, extraction of blood group substances and immunohistochemistry (PAP). All 3 methods gave essentially specific results for fresh bone tissue but with putrid bone tissue unspecific reactions were found predominantly with the absorption-elution and PAP techniques. In contrast, more specific reactions were obtained from the extracts although they were much weaker. From this it can be concluded that pure physical binding plays a substantial role in the unspecific reaction between antibodies and bone material. It is suggested that the relevant physical properties are altered by putrification.

ABO Blood-Group System↗

On the prognostic relevance of ego-psychopathology in schizophrenia: a 2.5-year follow-up.

Based on a calibration sample comprising 552 schizophrenic patients, ego-psychopathology was modelled in terms of three empirical scales. For this purpose, a special assessment instrument (EPIS) had been designed which measures the phenomena of self-experience in psychotic individuals. Within the scope of these investigations, a 2.5-year follow-up study was carried out with 85 schizophrenic patients. The principal goal of this study was to test the predictive power of typical patterns of self-experience with respect to social functioning. In order to analyse the homogeneity of the data multidimensional scaling and cluster analysis was employed. The results derived from the initial interview suggested a partitioning of the population into two extreme groups termed, according to our model, high-risk and low-risk cases. The predictive power of ego-psychopathology with regard to the social situation was then tested by comparing the outcome of both groups after 2.5 years. The analyses yielded no indication that there is a strong relationship between ego-psychopathology and social adaptation. Only a tendency could be found suggesting that subjects with few ego-psychopathological disturbances have a better occupational behaviour.

Adaptation, Psychological↗

Real-time multiprocessing of slit scan chromosome profiles.

The multiprocessor NERV and its application to slit scan flow cytometry is described. Up to 320 processors and 640 MBytes of RAM may be used in one VME crate, providing a computing power of less than or equal to 1300 MIPS. The multiprocessor is controlled by a host computer that provides a friendly user interface and comfortable program development tools. All hardware and software has been tested on a prototype NERV system with 5 processors. For a real-time classification/detection of normal and aberrant chromosomes, the centromeric index or the number of centromeres are computed or specifically labeled DNA sequences are detected. The program is partitioned into 60 tasks that can be executed concurrently. A total analysis time of less than 600 microseconds including system overhead will be achieved according to timing measurements which have been done for all individual tasks.

Algorithms↗

[The Borrelia titer in ENT diseases].

In 139 patients with facial paralysis, sudden hearing loss, vertigo, and lymphadenitis of the head and neck, the prevalence of borrelia burgdorferi serum antibodies was examined with the help of immunofluorescence assays for IgG- and IgM-antibodies, immunofluorescence assays after absorption of cross-reacting antibodies with treponema phagedenis, ELISA, and Western Blot. Six out of 22 patients with facial paralysis, 11 out of 72 with hearing loss, eight out of 45 with vertigo, and five out of 25 with lymphadenitis of the head and neck were seropositive. These patients were compared with a control group of 52 patients without any clinical signs of Lyme disease. The control group consisted of patients admitted for surgery of septal deformities (n = 19), squamous cell carcinomas (n = 27), and pleomorphic adenomas of the salivary glands (n = 6). In nine out of 52 patients in the control group, antibodies against Borrelia burgdorferi were detectable. According to Fisher's exact test, there was no statistical difference between the two groups as regards the prevalence of seropositive patients. Lyme disease is a doubtful major etiologic factor in facial paralysis, sudden hearing loss, or vertigo.

Adult↗

[Differentiation between in-life and post-mortem hemorrhage].

The determination of the time of haemorrhaging can be of substantial importance in the forensic practice. Histological, immunohistochemical and morphometric investigations were carried out on haemorrhages from animal experiments and from human pathological samples. Centrifugal topology, serum-erythrocyte discontinuity, topological arrangement of Fibrin formation and stabilisation of Factor XIII A were evaluated as criteria to define antemortal origin of haemorrhages.

Adipose Tissue↗

[Immunochemical and chromatographic determination of ABH antigens in compact bone tissue].

The identification of ABH antigens from compact bone tissue is known from many sources. The purpose of this study was to make a contribution to the localization of blood-group-active substances in compact bone tissue. A variety of preparation and identification methods were successfully used and compared. Samples were extracted from compact bone tissue, separated by HPTLC, and examined using the absorption-elution and PAP techniques. Additionally, the PAP technique was carried out on cryostat sections. Serologically active blood-group substances were consistently demonstrated in the organic components of the haversian canals.

ABO Blood-Group System↗

[Detection of glycosphingolipids of ABH and Le antigens on thin-layer plates using the PAP method].

Stroma from hemolyzed erythrocytes of blood groups 0, A1, B and A1B were obtained and subjected to butanol/phosphate buffer extraction. This extract was separated using HPTLC, and the ABH and Le substances were detected on the chromatogram using the PAP technique. The staining of the bands allowed specific demonstration of the serologically active glycosphingolipids present in the ABH and Le blood group substances. The antigens of the AB0 system showed a 3- to 12-band pattern. Each of the antigens Lea and Leb presented 3 bands. The slight differences in the levels of glycosphingolipids of equal chain lengths are probably due to differences in their chemical structures.

ABO Blood-Group System↗

[Clinical use of click evoked oto-acoustic emissions at the Freiburg ENT clinic].

Click-evoked otoacoustic emissions appear to be an efficient way to assess cochlear function in infants and neonates. A new technique developed by Bray and Kemp (1987) enables data to be gathered under clinical conditions. A total of 310 children aged between one day and five years were examined in a realistic clinical situation: 204 of them were admitted to the authors' outpatient department for evaluation of a hearing impairment and 106 were special-care babies or normal newborns. Otoacoustic emissions were successfully tested in 244 of these 310 children at the first attempt after performing behavioural tests. A classification of the emissions by the coefficient of the cross-correlation function and the frequency response spectrum was used. Emissions were observed in 95% (n = 181 ears) of the three- to five-year-old children with a mean behavioural threshold better than 20 dB. In 82% (40/49) of the special-care babies and in 89% (51/57) of the normal newborns a successful emission recording was be obtained. Such findings suggest that this technique for detecting emissions may be useful in early diagnosis of hearing impairments, especially when combined with simple behavioural tests.

Acoustic Stimulation↗

[Magnetic resonance tomography in preoperative analysis of chronic post-traumatic osteomyelitis].

Chronic osteomyelitis in 8 patients was studied preoperatively by magnetic resonance (MR) imaging and in part of them also by computed tomography (CT). Morphologic information about extraosseous and intraosseous changes was important for surgical planning. In long bones CT generally is superior delineating bone structures (sequestra and fragments of devitalized bone in the intramedullary cavity) and MR may be used as an adjunct for localizing extraosseous and intraosseous abscesses. In trabecular bones as the os calcis MR seems to be equivalent to CT.

Adult↗

[Sniff-induced negative pressure--a cause for the development of middle ear diseases?].

The significance of "sniffing" causing tubal dysfunction and thus leading to the development of cholesteatoma is discussed. We examined 244 healthy ears (18% sniff-positive), 21 ears with a traumatic perforation of the tympanic membrane (10% sniff-positive), 46 ears with chronic mesotympanic otitis (17% sniff-positive) and 40 ears with cholesteatoma (60% sniff-positive). Two different methods were used: on intact tympanic membranes the pressure chamber impedance method described by Munker-Pedersen (1972), and for perforated tympanic membranes a pressure transducer. Our results show that: (1) "sniffing" can cause negative pressure in the middle ear space; (2) the traditional concept of opening failure is no longer sufficient to explain tubal dysfunction; (3) sniff-induced negative pressure is a further possible cause of tubal dysfunction; (4) sniff-induced negative pressure seems to be an important factor in the development of cholesteatoma.

Adolescent↗

[Analysis of erythrocytic carrier molecules (glycosphingolipids) with ABO and Le specificity].

Membrane structures (stroma) were obtained from erythrocytes of various ABO and Le blood groups using a butanol/phosphate buffer extraction. The extracts were separated using thin layer chromatography and the ABO and Le antigens demonstrated directly on the chromatogram using the PAP-technique. Detection was carried out using either Ulex europaeus lectin or monoclonal antibodies. By this method the direct staining of the bands allowed a specific demonstration of the ABH and Leactive glycosphingolipids. A determination of the number of sugar residues is possible as well as the recognition of quantitative variants.

ABO Blood-Group System↗

[Lung function and symptoms in employees of poultry farms].

Environmental measurements were made in different types of poultry confinement buildings. Levels of total dust 1.6 meters above the ground averaged 5.0 mg/m3. Ammonia levels averaged about 13 ppm with peak values of about 50 ppm. To study possible respiratory problems of the people working in these confinement buildings, the ventilatory lung function was measured and an interrogation concerning respiratory symptoms was carried out by 26 (7 females, 19 males) poultry farmers. A very high prevalence (10 of 26) of obstructive ventilatory lung function changes was found. The FEV1 values of the exposed men were significantly lower than the predicted normal values (ECCS). An association between duration of exposure and pulmonary function exists.

Adult↗

The early development of Kraepelin's ideas on classification: a conceptual history.

Psychiatry still lives in a Kraepelinian world and scholarship on the work of Kraepelin has consequently been unhistorical. Selective exegesis of the various editions of his textbook has led to a rigid view of his contribution. However, Kraepelin lived and wrote during an important period of European intellectual history and his work can only be understood against this background. This paper analyses the development of his views in terms of the 'Research Programme' he planned early in his life and whose objective was the creation of a stable description and classification of the psychoses. This Kraepelin eventually achieved by longitudinally studying patient cohorts in terms of methodological criteria such as illness course and incurability. In the event, this methodology allowed him to identify by correlation 'clinical pictures' that both represented the 'essence' of the disease and provided a taxonomic criterion. Although avowedly atheoretical, Kraepelin thus managed to construct (influenced by Kahlbaum and Wundt) an empirical support for his Kantian categorization of the psychoses. A discussion of the cultural variables that moulded these ideas is included.

Germany↗