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Biomedical subjects

R Harzmann

Publications and source records attributed to R Harzmann.

At least 91 records · Page 5Linked to original sources
PubMed1978

[Local high-frequency hyperthermia of the Brown-Pearce carcinoma in the urinary bladder of rabbits (author's transl)].

The effect of a conductive high-frequency hyperthermia on a model tumor in the urinary bladder of rabbits (Brown-Pearce Carcinoma) was studied at a temperature of 43 degrees C, and with an application time of 30 min. The frequency used was 500 kHz, wattage 30-300 and wavelength 600 m. This resulted in the homogeneous warming of the urinary bladder tissue, in contrast to the results obtained when warm water was injected. Essential test results included: (1) a temperature gradient of max. 6.7 degrees C from the tumor center to the lumen of the urinary bladder, the tumor favoring the higher temperatures; (2) a prolongation of the survival time for animals with heat-treated tumors as opposed to the control animals. After transplantation heat-treated tumors evolved to receptor animals considerably less often than did untreated tumors.

Animals↗
PubMed1978

[Indirect lymphography of the urinary bladder in animal experiments (author's transl)].

Of three contrast media injected interdigitally and submucosally as well as instilled into the bladder, Lipiodol UF (particle size of over 15 micron) and the experimental compound AG 52-315 were not resorbed. Another experimental compound (AG 60-99) with an iodine content of 20% and a particle size of ca. 3,5 micron produced, when injected interdigitally, good contrast of the popliteal lymph nodes in all cases (n = 5). Instillation of the same contrast medium into the bladders of five dogs yielded subdued contrast of the paravesicular lymph nodes in one case. Of still another five animals, two showed contrast of the inner iliac lymph nodes after submucosal infiltration of the bladder mucosa with AG 60-99. In all cases (n = 15) inflammatory reaction with necrotic formations were observed. Resorption of the contrast medium was accomplished by heating at 39 degrees C, and was not improved by addition of Hyaluronidase. Because of the low local tolerance of the contrast medium preparation, this successful experiment in indirect lymphography of the urinary bladder of animals cannot be applied clinically.

Animals↗
PubMed1978

[Animal experimental and clinical experiences with carbon polymer stomas].

Biocarbon implants consist of 99.9% pure carbon and are characterized by chemical inactivity and good tissue compatibility. Biocarbon was used for subfascial implantations, as well as coecostomies, ileostomies and cystostomie on mongrel dogs. The most important clinical results was the good healing over of the material without adverse reaction. The cystostomies showed only a very slight tendency to form incrustations. Drainage was watertight without signs of leakage. The satisfying results with two patients who were provided with a cystostoma are reported and further uses of the procedure, such as ureterocutaneostomy, iliac and colonic conduit, are discussed.

Aged↗
PubMed1977

Ureteroneocystostomy without dissection of the submucosal tunnel.

A technique of ureteroneocystostomy with fixation of the ureter to the bladder musculature denuded from the mucosa was studied in dogs. The intravesical portion of the ureter shrank to half its original length after the operation. This portion preserved its muscular structure and was overgrown by the bladder mucosa to more than half its circumference. The submucous canal thus formed for the ureter prevented reflux in every animal. The technique avoids the formation of strictures. It is recommended if direct dissection of a submucous canal is impracticable.

Animals↗
PubMed1976

[Serum acid phosphatase levels following prostatic massage (author's transl)].

We find an elevation of serum acid phosphatase levels 5 min after prostatic massage in only 10% of patients with prostatic adenoma. This increase is caused by stored prostatic secretion being pressed into the blood vessels. 60 min later these serum levels decrease. With some other patients a slower increase of phosphatase levels occurs; this increase, however, lasts for hours. This kind of increase is caused by prostatic fluid being forced into the interstitium where it is slowly absorbed. A combination of both kinds leads to a curve with two peaks; this could be demonstrated in two cases. No difference was seen in reaction of total acid phosphatase and prostatic phosphatase levels. The increase of phosphatase levels following prostatic massage was no sign of prostatic carcinoma.

Acid Phosphatase↗
PubMed1975

[Reversible hyperuricemia in case of ureteral colics (author's transl)].

On about one fourth of the patients ureteral colics caused by oxalate and phosphate calculi lead to a reversible hyperuricemia. This result seems to be important, because we might wrongly diagnose a uric acid calculus. The reason for hyperuricemia is a temporary diuretic disturbance of the uric acid. It cannot be explained by the functional loss of the obstructed kidney, because a nephrectomy does not change the uric acid level. As a possible reason we suppose a ketose by food deficiency and vomiting caused by renal colic.

Blood Urea Nitrogen↗
PubMed1975

[Perineal and transrectal needle biopsy of the prostate (author's transl)].

On 254 biopsies of the prostate with the tru-cut needle the approach was either rectal or perineal depending on even or uneven dates of birth. The rectal approach showed wrong negative results a little more frequent than the perineal approach. Feverish complications were 6 times more often by rectal than by perineal approach. Additionally the rectal biopsy was complicated by serious bleedings out of the hemorrhoidal vessels or periprostatic veins. Based on the investigations you should chose the perineal approach as the routine method and use the rectal biopsy only for special indication.

Adult↗