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Biomedical subjects

R Happle

Publications and source records attributed to R Happle.

At least 361 records · Page 20Linked to original sources
PubMed1976

[Gangrenous pyoderma and IgA-paraproteinemia].

A gammaAchi--paraproteinemia was found in a 73 year-old female patient with pyoderma gangraenosum. Since the paraporteins hitherto observed in pyoderma gangraenosum predominantly belong to the IgA class, a relationship may exist between pyoderma gangraenosum and this type of paraproteinemia.

Aged↗
PubMed1976

[Hypomelanosis cutis ITO (author's transl)].

Report on a 9 year old girl exhibiting the typical features of Ito's syndrome: systematized bilateral depigmented nevus associated with various nonspecific dysplasias. The pathogenesis is not known. The syndrome geems to be transmitted by an irregularly dominant gene.

Biopsy↗
PubMed1976

[Ito's syndrome (incontinentia pigmenti achromians)].

Ito's syndrome is a distinct entity characterized by bilateral systematized linear depigmentations denominated by Ito as "incontinentia pigmentiachromians". The syndrome includes a variety of anomalies predominantly affecting the central nervous system, the eyes, and the muscular-skeletal-system. The patient described in this paper was a 26 year old man suffering from a sever scoliosis. This anomaly had not been mentioned in previous case reports.

Abnormalities, Multiple↗
PubMed1975

[Spontaneous regression and leukoderma in malignant melanoma].

In four patients with superficial spreading melanoma, partial spontaneous regression and/or leukodermas of different appearance occurred. In two patients leukoderma appeared within the central area of the primary tumor; one of whom developed, in addition, vitiligo elsewhere on the body. In a further case the melanoma exhibited a depigmented halo resembling Sutton's nevus. Presumably, these leukodermas represent an epiphenomenon of the specific immunological reaction between the host and the melanoma.

Adult↗