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Biomedical subjects

R Gupta

Publications and source records attributed to R Gupta.

At least 865 records · Page 48Linked to original sources

Chromosomal abnormalities in protein-calorie malnutrition.

Cytogenetic studies were carried out in five children suffering from moderate to severe protein calorie malnutrition and five healthy controls, using direct preparations of bone marrow using conventional techniques. In the control group there were two abnormalities out of 152 plates analyzed, and in the malnutrition group there were 16 out of 186. This difference is statistically significant, P less than 0.005, implying that chromosomal abnormalities are more frequent in protein calorie malnutrition.

Bone Marrow Cells↗

A double blind comparison of lithium carbonate and ludiomil in the prophylaxis of unipolar affective illness.

A double-blind prospective study was carried out comparing the prophylactic effect of maprotiline and lithium carbonate over a period of 1 year in patients suffering from recurrent affective disorders. The average Affective Morbidity Index was lower, but not significantly so, in patients treated with lithium. A further analysis based on dividing patients into those with no affective morbidity and those who showed some affective morbidity during the study, demonstrated lithium carbonate to be significantly superior to maprotiline in both the group as a whole and in unipolar depressives.

Adult↗

Mianserin hydrochloride: a novel antidepressant.

The antidepressant activities of mianserin hydrochloride were investigated and compared with those of amitriptyline. The therapeutic efficacy of the two drugs appeared similar, but the incidence of side-effects was significantly higher with amitriptyline. Plasma levels of mianserin were determined during the trial and were not related to the therapeutic activity of the drug.

Adjustment Disorders↗

Peripheral argon laser iridectomy in narrow-angle glaucoma.

Gas argon laser peripheral iridectomy was attempted as an alternative to surgical peripheral iridectomy in the treatment of acute angle-closure glaucoma and the prophylactic treatment of fellow eyes. Success was achieved in eyes with a blue iris if sufficient energy was given to achieve a permanent red reflex. Reasons for failure in eyes with a heavily pigmented iris are discussed. The procedure must be greatly improved before surgical peripheral iridectomy is superseded as the treatment of choice.

Argon↗

Granulopoietic activity in Felty's syndrome.

The levels of urinary and serum granulopoietic factor have been determined in nine patients with Felty's syndrome and compared with similar levels in patients with rheumatoid arthritis without Felty's syndrome and patients with neutropenic disorders of other causes. These studies have shown that urinary and serum levels of colony stimulating activity (CSA) in patients with Felty's syndrome are low (mean urine CSA 10.0 and serum CSA 4.0) when compared to patients with neutropenic disorders without rheumatoid arthritis (mean urinary CSA 26.8 and serum CSA 9.4). These findings suggest that Felty's syndrome may be, in part, the result of decreased production or activity of granulopoietic factors rather than due simply to increased granulocyte destruction.

Adult↗

Cataract aspiration-irrigation. Modified needle-tubing-handle combination for push-pull machine.

A modification of the needle-tubing combination for the push-pull machine used for aspiration-irrigation of congenital and traumatic cataracts, is described. The new needle-tubing-handle combination is advantageous in that the incorporated handle makes the insertion and maneouvring in the anterior chamber easier and also the whole combination can easily be autoclaved as silastic tubing is used.

Cataract Extraction↗