One year's experience in a drug-dependence clinic.
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Biomedical subjects
Publications and source records attributed to R Gardner.
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In ten patients with hypothyroidism the adrenal response to stimulation with tetracosactrin was found to be normal, and to be unchanged after they had been treated with thyroxine. Though the response to insulin hypoglycaemia was less in the hypothyroid phase, it was never outside the normal limits. Hence it seems unlikely that the adrenal response to stress is appreciably lowered in hypothyroidism.
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This article reviews the physiology and pathophysiology of selected endocrine glands. The common presenting clinical signs and symptoms are reviewed, and the initial laboratory tests that may establish the diagnosis are recommended. Diagnosis and management of hypothyroidism, hyperthyroidism, hyperparathyroidism, hypoparathyroidism, pituitary disorders, diabetes mellitus (types I and II), hypoglycemia, and disorders of the adrenal cortex are discussed. The clinical management of the most commonly encountered endocrine disorders seen in the primary care setting is described, and pharmacologic considerations are underscored.
In light of a 10-year infant mortality crisis in Boston, a comprehensive public health approach was undertaken in which an extensive community-based needs assessment was used to develop a citywide maternal and child health improvement agenda. On the basis of the needs assessment, recommendations were made calling for community-based perinatal initiatives and midwifery services as critical elements in care for underserved communities and enhancement of perinatal services. A case description of one perinatal initiative illustrates the challenges of public health practice and describes a practice setting in which midwives provided leadership and guidance by using an interdisciplinary team approach in the implementation of a community empowerment project.
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Ten adult subjects, selected for good dream recall and ability to produce spontaneously fine limb movements in the laboratory, reported their last dream experience after awakenings from REM sleep during various limb movement and no movement conditions. The reports were rated for amount and girdle location of dreamed actions by judges blind to the awakening condition. There was a significant correlation between the number of girdles moving before awakening and the amount of dreamed action. Also, when dreams from single girdle movement awakening conditions were examined, the girdle active before awakening was dreamed as moving to a significant degree.
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This article examines the psychological needs of neuro-oncology patients and their families and presents two case histories which illustrate the way in which patients and their families can be brought to terms with their situations through skilled nursing intervention.
This report describes a rare case of multiple intracranial, extradural chloromas. A five year old African American male presented with headache, fever, and vomiting. The peripheral blood smear showed myeloblasts with Auer rods. The CTscan of the brain showed three intracranial, epidural lesions as well as soft tissue masses in the retroorbital region and sphenoid sinuses. CTscan of the chest showed two paraspinal epidural thoracic masses. Pathology of the epidural intracranial mass revealed a granulocytic sarcoma. Cytogenetic analysis showed simultaneous occurrence of t(8;21) and trisomy 8. Following induction therapy, he is now in complete remission.
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