Equivalence of various levothyroxine preparations.
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Biomedical subjects
Publications and source records attributed to R G Fischer.
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Simplifying drug regimens is one method of improving patient compliance. Medications originally administered several times a day are now reported to maintain 24-hour effectiveness on once-daily administration. In many cases this technique of administration results in the use of less expensive medication, an improvement in compliance, and even decreased side effects. All patients may not be controlled or tolerate increased intervals between drug doses. Interpatient variation dictates that physicians closely monitor their patients when prescribing new or unapproved regimens of drug therapy.
Patient administration errors in the use of beclomethasone dipropionate aerosol are frequent. Asthmatics once labeled "treatment failures" on this aerosol may only need adequate consultation to achieve therapeutic results. Pharmacists should monitor for patient noncompliance and provide instruction and follow-up on the use of beclomethasone dipropionate aerosol. Common administration errors associated with this drug are described, along with information patients should receive to obtain optimal benefits.
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Diabetic patients are traditionally taught to discard plastic syringe/needle units after a single use and to employ aseptic technique for administering insulin injections. We surveyed 87 diabetic outpatients for compliance with aseptic recommendations. We then studied prospectively the effects of reusing disposable syringes in 56 diabetic patients who reused syringes a mean of 6.6 times for 8.3 months and an aggregate of 23,664 injections. Almost half (49%) of diabetic patients in a combined university clinic and private practice reused supposedly disposable insulin syringes a mean of 3.9 times. Compliance with standard aseptic precautions was poor, with only 29% of patients following recommended practices. No adverse effect of syringe reuse was identified. The authors conclude that diabetic patients frequently reuse disposable syringes, without apparent harmful effect.