Search PubMed⌕ Search

Biomedical subjects

R Fuchs

Publications and source records attributed to R Fuchs.

At least 91 records · Page 5Linked to original sources
PubMed1984

[Rationalization and limits of diagnostic and operative measures in invasive cholestasis diagnosis (percutaneous transhepatic cholangiography) in primary medical care].

In a case of jaundice PTC enables the surgeon to detect its mechanical cause without further delay. This method is especially helpful in smaller hospitals without CT or even sonographic equipment. Explorative laparotomy is no longer necessary. An immediate decision can be made whether to perform a palliative or curative procedure or only to install a percutaneous bile drainage.

Biliary Tract Neoplasms↗
PubMed1979

[Acute mature myelocytic leukemia as a form of the myeloproliferative syndrome].

On the basis of five observations of adult patients with the clinical feature of mature cellular leukaemia which proved to be therapy-refractory and which was characterized by a rapid course is referred to the necessity of the differentiation of such cases from the classical myeloic leukaemia. The cardinal symptoms of this type of disease, which probably is identified with the cases described in literature as atypical chronic myelosis, as paraneutrophil leukaemia or as acute myelofibrosis, and also shows common features with the juvenile chronic myelosis, are, apart from the mature cellular differential blood picture a short life expectancy (less than 1 year), an initial thrombocytopenia, a normal or increased activity of the alkaline granulocyte phosphatase, the lack of Ph1-chromosome as well as the bad therapeutic reaction to busulfan. The observation of the simultaneously existing fibroses of the bone marrow as well as of the final increase of immature blasts induced the classification of the clinical picture as a special form of the myeloproliferative syndrome.

Acute Disease↗
PubMed1979

[Experiences with primary and secondary laparotomy with splenectomy in Hodgkin's disease].

The explorative laparotomy with splenectomy belongs under adequately strong indication to the standard techniques of the dilated diagnostics and stage subdivision of lymphogranulomatosis. 61 patients of the Medical Academy Magdeburg were exploratively laparotomised from 1974--1978, of them 38 patients primarily before the beginning of the therapy and 23 patients secondarily 1--8 years after therapy. Changes of the stages before and after laparotomy, relations between affection of the spleen and histological type and primary histology, respectively, as well as weight of the spleen are discussed, postoperative complications are explained and adequate conclusions rendered.

Diagnostic Techniques, Surgical↗
PubMed1979

[Therapy of malignant non-Hodgkin's lymphoma].

Up to now the results of the therapy of malignant non-Hodgkin lymphomas are not satisfactory. In order to improve these results decisively it is necessary to develop and to test therapeutic strategies on standardised diagnostic basis. On the basis of the histological classification after Kiel of the malignant non-Hodgkin lymphomas and the clinical stage subdivision of the lympho-granulomatosis after Rye (for the malignant non-Hodgkin lymphomas modified by Musshoff) in the present paper therapeutic recommendations are given which are based on proved therapeutic regimes.

Brain Neoplasms↗
PubMed1979

Human tonsil lymphocytes in the transfer of cell-mediated immunity.

Peripheral blood lymphocytes have the ability to transfer cellular immunity. In this study, we investigated whether human tonsil lymphocytes could transfer cellular immunity. Human tonsil lymphocyte ultrafiltrates, after separation through gel filtration, showed five fractions in Sephadex-G-10, as well as four in Sephadex-G-25,4. The extracts and the fractions have characteristic biochemical as well as biological properties. The biological activity of ultrafiltrates from human tonsil lymphocytes was compared with the activity of ultrafiltrates prepared from human peripheral blood lymphocytes, for identification studies of a 'Transfer Factor' from human tonsils. Ultrafiltrates prepared from human peripheral blood lymphocytes (Ascher et al., 1976) and tested, showed similar biochemical and biological properties.

Humans↗
PubMed1978

Metabolism, oxygen transport, and erythropoietin synthesis in the anemia of thermal injury.

The relationship between metabolism, oxygen transport, and anemia was assessed in burn patients. A significant negative correlation was found between erythrocyte 2,3 DPG, the major modulator of oxygen transport, and erythropoietin synthesis. Simultaneous bioassay and radioimmunoassay for erythropoietin revealed elevated values in the anemic burn patients. Elevated 2,3 DPG values during convalescence from thermal injury may remove the "anemic hypoxia" stimulus to erythropoieitn production, resulting in persistence of the anemia.

Adult↗