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Biomedical subjects

R Fischer

Publications and source records attributed to R Fischer.

At least 685 records · Page 38Linked to original sources
PubMed1979

[Pathology and classification of colorectal polyps].

This survey deals with the principles of classifying colorectal polyps and with the fundamentals of anatomic pathology of these growths. In this connection, the epithelial neoplastic types, which are now known as adenomas, are of particular importance in so far as they are the potential precursors of carcinomas of the colon and rectum (""adenoma cancer sequence''). The polypectomy specimen alone enables definite histo-pathological diagnosis.

Adenocarcinoma↗
PubMed1978

[The importance of echography in the differential diagnosis of renal insufficiency (author's transl)].

Experience with echographic investigation of the kidney and the urinary efferent system in the diagnosis of renal insufficiency is reported. Taking into account a number of criteria (size, differentiation from the surrounding tissues, position of the kidney in relation to neighboring organs and to the body surface, mobility or change of shape on respiration, on altehe evaluation of the nephroechographic findings an attempt is made to rationalize the applicatinon of further diagnostic measures. The method is recommended both for the initial diagnosis of renal insufficiency and for the supervision of patients with confirmed renal insufficiency.

Adolescent↗
PubMed1978

Histochemical methods for the demonstration of Thomsen-Friedenreich antigen in cell suspensions and tissue sections.

1. Three different methods are described for the visualisation of the Thomsen-Friedenreich (TF) antigen on cell suspensions, formalin-fixed and paraffin embedded or frozen tissue sections: a) Rosette formation with chicken and sheep erythrocytes. b) Fluorescence-microscopy with fluorescein labelled peanut agglutinin. c) Autoradiography with 3H-labelled peanut agglutinin. 2. The TF antigen was shown, as far as presently investigated, to be exposed on various blood cells, glomerula of the kidney and normal mammary gland after neuraminidase treatment. Mammary gland was also shown to possess TF receptors without prior treatment with neuraminidase. 3. The exposure of this cryptantigen can be brought about by bacterial or viral neuraminidase and is followed by an antigen/antibody reaction, which can lead to possible pathological consequences.

Animals↗
PubMed1978

Carcinoembryonic antigen follow-up and selection of patients for second-look operation in management of gastrointestinal carcinoma.

A long-term postoperative carcinoembryonic antigen (CEA) follow-up study is carried out with patients having undergone primary resection of histologically proved adenocarcinomas of the gastrointestinal tract. Up to now, 122 patients who underwent curative resections, as judged from the situs and the results of histologic examinations, were followed up for tumor recurrence by computerized CEA surveillance diagrams and clinical diagnostic methods. In the cases of tumor recurrence the rise of the CEA level preceded a positive clinical diagnosis by a mean of 4 months. On the basis of the CEA time course, we selected 28 patients for second-look surgery. In all cases proof of recurrence of the disease was obtained. A local recurrence correlating with a slow CEA rise was generally resectable, metastases correlating with a rapid CEA rise were only in some cases resectable, provided that second-look surgery was carried out without delay.

Adenocarcinoma↗
PubMed1978

[Aneurysms of the splenic artery--pathogenesis and clinical study (author's transl)].

The pathogenesis and clinical study of the aneurysms of the splenic artery will be represented from the available literature. Retrospective from the literature 144 cases were taken into consideration and a further 6 added on. The problems of the diagnosis will be discussed, the importance of the selective angiography as the only possible means for a definate pre-operative diagnosis emphasized. Different methods of operation will be described, in which the removal of the aneurysm together with a splenectomy represents the method of choice.

Adult↗