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Biomedical subjects

R F Edlich

Publications and source records attributed to R F Edlich.

At least 217 records · Page 12Linked to original sources
PubMed1982

Polyethylene glycol intoxication in burn patients.

Unexplained increases in the anion gaps and serum osmolalities were observed in 3 burn patients who died following treatment with a polyethylene glycol-based burn cream. Toxicity due to absorption of polyethylene glycol was suspected after other causes had been excluded. Ethylene glycol was found in the circulation and the 3 patients died in acute renal failure. All the patients were acidotic with increased anion and osmolal gaps. This syndrome was similar to the more common poisoning with ethylene glycol but also included an increased serum calcium with a concomitant decrease in the ionized calcium. The cause of this high 'calcium gap' appeared to be binding of calcium by dicarboxylic acid metabolites of polyethylene glycol. These findings were the same as those found in rabbits treated with polyethylene glycol.

Acute Kidney Injury↗
PubMed1982

Damage to tissue defenses by a topical anesthetic agent.

The purpose of this study was to determine the effect of a topical application of a solution containing 0.5% tetracaine, 1:2,000 epinephrine, and 11.9% cocaine on the wound's ability to resist infection. In this experimental study, this solution potentiated the development of wound infection. This effect can be explained by its vasoconstrictive action limiting access of the cellular defenses to the bacteria on the wound surface.

Administration, Topical↗
PubMed1982

Computer-aided emergency telecommunications for the deaf.

Computer-aided telecommunications provide deaf teletypewriter users with 24-hour toll-free access to emergency services. An interface and software link the deaf caller's teletypewriter (TDD) with a microprocessor by reducing and inverting voltage levels between the two devices. This system facilitates rapid transmission of linguistically controlled triage questions to meet the communication needs of deaf patients.

Communication Devices for People with Disabilities↗
PubMed1982

Epidemiology of serious burn injuries.

The incidence of serious burn injuries has been determined for the Commonwealth of Virginia during a 21 month period. The data set included all patients with burn injuries who entered the hospital and were considered to be in serious enough condition to require treatment in a hospital. The risk for burn injury was calculated by age, race and sex. Examination of the date revealed large differences in the magnitude of age-specific incidence rates between men and women and the white and nonwhite population. Differences in the economic status of the population may explain a large proportion of the variation in the crude burn rates.

Adolescent↗
PubMed1982

Prediction of burn mortality.

The present investigation was undertaken to compare the accuracy with which two clinical rules of thumb and an empirically derived quantitative index of burn severity classify burn victims into categories of risk to survival. all three assessment protocols correctly classified the majority of the survivors. However, the quantitative index of burn severity, the Abbreviated Burn Severity Index, was superior to the Baux and the modified Baux clinical rules of thumb in predicting fatalities. It was concluded that the Abbreviated Burn Severity Index was nearly as easy to use as the clinical rules of thumb, yet more accurate and specific in describing outcomes for the victims of a burn injury.

Adolescent↗
PubMed1981

An educational training program for the care at the site of injury of trauma to the central nervous system.

The treatment of head and spinal cord injuries must be directed towards prevention of secondary insults which will increase the extent of permanent disability. Improved extrication techniques at the scene of the accident, earlier recognition and treatment of complications and improved transfer management have all reduced the acute morbidity and mortality of injuries to the central nervous system. At the University of Virginia we have implemented a comprehensive training program in the acute care of the head and spinal cord injured patient for Emergency Medical Technicians (EMT), nurse, community referring physicians, and house staff within the medical center. A booklet, prepared for care at the site of injury, outlines the assessment, care and intervention with the head and spinal injury patient for the EMT. Another booklet provides guidelines for care of the patient in the emergency department. Included here are instructions in respiratory care, adequate circulation and spinal splinting. The greatest emphasis is placed on the history and physical examinations, which documentation of the extent of neurologic deficit, including the Glasgow coma scale. Data on 900 pre-hospital calls by volunteer EMTs demonstrate a 90% compliance in basic life support skills outlined in the educational program. A similar compliance has been achieved with referring physicians and house staff in the medical center, in the acute management of the CNS injured patient, due primarily to this educational program and increase in the optimal care of these patients has resulted.

Accidents↗