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Biomedical subjects

R E Page

Publications and source records attributed to R E Page.

At least 73 records · Page 4Linked to original sources
PubMed1979

Surgical correction of the hand in epidermolysis bullosa dystrophica.

Epidermolysis bullosa dystrophica (polydysplastic type) is a rare congenital skin anomaly which, in the hands, because they are exposed to repeated trauma, results in a severe "mitten"-like deformity. Functional benefit was obtained in three patients by separation of the digits and application of split-thickness grafts. Wolfe grafts or "split-off" (epidermis) grafts. Arthrodesis of the interphalangeal joints and filleting of the little finger to provide a flap which could be turned in to the palm, resulted in an improvement in hand function.

Adolescent↗
PubMed1978

Height and weight gain after total correction of Fallot's tetralogy.

In a consecutive series of 100 cases of Fallot's tetralogy undergoing total correction, the mean birthweight was found to be just below the 50th centile. Blalock-Taussig or Waterston shunts were performed in 45 patients. Before their shunt operations a significant number of patients had become retarded in height and weight development but after the shunt operations many patients showed accelerated height and weight gain. Of the 73 patients followed up 2 years after correction, 23 had experienced accelerated development in both weight and height, but 11 patients remained on or below the 3rd centile for weight and height. In terms of the age at shunting, the oxygen saturation immediately before total correction, the age at total correction, the number of ventriculotomy patch repairs, and the post-correction ventricular pressure ratios, no significant difference could be detected between those 23 patients who had undergone accelerated development and those 11 who had remained retarded. More shunts, particularly of the Waterston type, were performed in the retarded group.

Adolescent↗
PubMed1977

Superficial sepsis: the antibiotic of choice for blind treatment.

When all cases of superficial sepsis were considered together Staphylococcus aureus was the most frequently encountered organism. Various anatomical sites were considered separately and it was found that the axilla and breast were particularly prone to infection by Staph. aureus. The incidence of infection by coliform bacili in Bartholin's and anorectal abscesses was significantly higher than in abscesses elsewhere. The importance of these observations in relation to antibiotic therapy is discussed.

Abscess↗
PubMed1976

A practical reappraisal of the anatomy of the extrahepatic bile ducts and arteries.

Two hundred and five dissections of the extrahepatic biliary tree have revealed that although the anatomy of this area is remarkably variable there are obly three important vascular and five important ductal anomalies (the former occurring much more frequently than the latter). Each anomaly is, however, easily recognized at operation. A higher incidence of anatomical anomalites was found in patients with gallstones compared with those without and in women than in men, and there was a remarkably low incidence of accessory hepatic ducts overall. The significance and practical implications of these findings are discussed.

Bile Ducts↗
PubMed1975

Simplified computer-aided diagnosis of acute abdominal pain.

A simplified version of a system for computer-aided diagnosis of acute abdominal pain has been tested by "new" personnel unfamiliar with the previous system. After a two-month learning period the system proved more accurate in its diagnoses than the unaided clinician, and during the first five months of using the system the unaided clinicians' accuracy rose from 73% to 84%. When computer "feedback" was withdrawn the clinicians' diagnostic accuracy reverted towards the previous, "unaided" level. These findings further validate the concept of the computer as a potentially valuable diagnostic aid but indicate that a training period and computer feedback are important factors in its 4 use.

Abdomen, Acute↗
PubMed1975

Primary gastric tuberculosis: a case report.

A case of primary gastric tuberculosis is reported in a 34-year-old Negro male. The difficulty in diagnosis is emphasized. Surgical resection with postoperative anti-tuberculosis chemotherapy was followed by satisfactory recovery.

Adult↗
PubMedDate not supplied

A controlled study comparing the conventional treatment of idiopathic anorectal abcess with that of incision, curettage and primary suture under systemic antibiotic cover.

The treatment of anorectal abscess by deroofing and packing on an initial inpatient basis has been compared in a controlled trial with that of incision, curettage and primary suture under systemic antibiotic cover in the Accident and Emergency Department. Over a three-year period 219 patients with anorectal abscess were randomly allocated to one or other treatment and subsequently followed up in a rectal clinic. In terms of the time taken for complete healing and the periods lost from work postoperatively, the method of incision, curettage and primary suture under systemic antibiotic cover was found to be significantly superior, without any increased risk of recurrence of the abscess or of subsequent fistula formation.

Abscess↗
PubMedDate not supplied

The double cross plasty: a new technique for nasal stenosis.

Atresia and stenosis of the anterior nares is caused by a lack of the normal mucous membrane lining the nasal vestibule. The condition may be congenital but is usually acquired. In most cases the external contour of the nose is not affected but an extensive deficiency of the mucosal lining may alter the shape of the cartilagenous part of the nose. The width of the obstruction, the state of the surrounding lining and the degree of the external deformity are the main factors to be assessed in any attempt at surgical correction. A new technique is presented which has successfully corrected severe unilateral stenosis in two children.

Humans↗
PubMedDate not supplied

Quantitative trait loci influencing honeybee alarm pheromone levels.

Quantitative trait loci (QTL) mapping procedures were used to identify loci that influence the levels of alarm pheromones found in the stinging apparatus of worker honeybees. An F1 queen was produced from a cross between a queen of European origin and a drone descended from an African subspecies. Haploid drones from the hybrid queen were individually backcrossed to European queens to produce 172 colonies. Samples of stings were taken from backcross workers of these colonies. Alarm pheromone levels were determined by gas chromatography. RAPD markers were scored from the haploid drone fathers of these colonies. The multiple-QTL model (MQM) of MapQTL was used to identify QTLs that influence the levels of four alarm pheromone components. Seven independent, potential QTLs were identified with LOD scores greater than two, and one at LOD 1.88. We identified one QTL for n-decyl acetate, three for n-octanol, four for isopentyl acetate, and one for hexyl acetate. One region of linkage group XI shows a strong influence on body size and the levels of three alarm pheromone components. This locus explained 40% of the variance for the amount of n-decyl acetate (LOD 6.57). In general, the QTLs influencing alarm pheromone levels were independent of previously identified loci that influenced the stinging behavior of these colonies. The only exception was a potential locus influencing levels of n-octanol, which was inversely correlated with stinging behavior.

1-Octanol↗