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Biomedical subjects

R Dominguez

Publications and source records attributed to R Dominguez.

At least 73 records · Page 4Linked to original sources

Uncomplicated trigonocephaly. A radiographic affirmation of conservative therapy.

Trigonocephaly is a relatively rare deformity of the skull characterized by triangular prominence of the bones of the forehead and orbital hypotelorism. Long-term results in a group of patients with clinical and radiographic follow-up are analyzed, the radiographic findings reviewed, and possible etiologies discussed. The etiologic relationship between premature synostosis of the metopic suture and trigonocephaly is questioned. Uncomplicated trigonocephaly is a self-limited, self-correcting deformity, and a normal cosmetic appearance develops without surgical treatment. Surgical craniectomy as treatment for uncomplicated trigonocephaly is not indicated on the basis of the authors' experience.

Female↗

Abnormal intestinal motility in gastroschisis.

The authors describe abnormal intestinal motility with a very slow transit time in eight children with gastroschisis. Other abnormal findings include malrotation, dilatation, and fixation of the loops of the bowel.

Abdominal Muscles↗

Left aortic arch with right descending aorta.

A left aortic arch with a right descending aorta is a rare congenital anomaly. The radiographic findings in 13 previously described cases and three additional cases are discussed. Characteristic findings on the plain radiograph and esophagram can usually obviate the need for aortography. The anomaly was associated with a vascular ring in at least four and probably five of the 16 patients. Additional and more complex studies may be needed in patients with suspected symptomatic vascular rings.

Aorta↗

Induction of precocious puberty in newborn female guinea pigs by a positive feedback action of estrogens.

The existence of a positive feedback of estrogen on the gonadotrophin-releasing mechanism at birth, was tested in the female guinea pig. Estradiol benzoate (100 ng during the first 5 days of life) or HCG (100 RU during the first 5 days of life) induced a true precocious puberty, with similar characteristics to the control animals (60% of the animals ovulated at puberty age: corpora lutea present at the ovaries). The uterus was larger in ovulating than in nonovulating animals. Reserpine (2.5 mg/kg) on 15, 17 and 19 days of age did not modify the precocious puberty induced by estradiol at birth. It is concluded that exogenous or endogenous estrogen (induced by exogenous gonadotrophin administration) have a positive feedback action on the newborn female guinea pig to release gonadotrophin and develop puberty. These results are very different than those observed in the rat and differences can be related to the stage of somatic and nervous maturation attained by the animals at birth.

Animals↗

Intrauterine diagnosis of hydranencephaly by magnetic resonance.

Magnetic resonance imaging (MRI) was used to confirm an ultrasound diagnosis of hydranencephaly in utero. MRI provided an accurate anatomical assessment, influencing the pregnancy management. The result supports previous reports suggesting that MRI may be a useful complement to ultrasonography in intrauterine diagnoses.

Adult↗

MRI findings in osteofibrous dysplasia.

A case of osteofibrodysplasia of the long bones in a 4-year-old girl is reported with ipsilateral tibial and fibular involvement. The radiological pattern of the lesions suggested fibrodysplasia but not their MRI signal characteristics. This diagnostic imaging mismatch and the bifocality of the lesion were the tell-tale indications for the confirmatory bone biopsy yielding osteofibrous dysplasia of Campanacci.

Child, Preschool↗

Diffuse neonatal hemangiomatosis: imaging findings in two patients.

Diffuse neonatal hemangiomatosis is a rare condition in which cutaneous and visceral hemangiomas may coexist. Intra-abdominal involvement occurs commonly and, if untreated, may result in high-output cardiac failure and other life-threatening conditions. We report two neonates with this disease and discuss the radiographic findings and the role of vascular embolization in the treatment of hepatic hemangiomatosis.

Abdominal Neoplasms↗