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Biomedical subjects

R D Price

Publications and source records attributed to R D Price.

At least 37 records · Page 2Linked to original sources

Pulmonary edema associated with upper airway obstruction in dogs.

In order to evaluate the effect of acute upper airway obstruction upon pulmonary edema (PE) formation, we studied seven dogs that were subjected to inspiratory obstruction for three hours. Hypoxia was avoided by the administration of supplemental oxygen during the study period. Six dogs developed pulmonary vascular congestion, and four developed histologic findings of PE. Inspiratory intrapleural pressure decreased to -28 +/- 4 mmHg in dogs that developed PE and to -23 +/- 2 mmHg in dogs that did not. Transmural pulmonary artery pressure and pulmonary artery wedge pressure did not increase significantly. Central venous pressure during inspiration (CVPi) increased in all dogs, and CVP at end expiration (CVPe) was significantly higher in dogs with PE. Dogs that developed PE experienced a decrease in cardiac output and an increase in systemic vascular resistance. Furthermore, alveolar ventilation declined in dogs with PE, ultimately resulting in ventilatory failure. Pulmonary edema formation was not preceded by an increase in pulmonary vascular pressures but was associated with higher CVP, pulmonary vascular congestion, and hypercarbia.

Acute Disease↗

Lice on helmeted guinea fowls at five localities in South Africa.

A total of 234 helmeted guinea fowls, Numida meleagris coronata, were examined for lice at five localities in South Africa. These were the Mountain Zebra National Park in the eastern Karoo, Cape Province; the Andries Vosloo Kudu Reserve and the farm Bucklands, in Valley Bushveld, eastern Cape Province; the Bontebok National Park, south-western Cape Province; and the southern part of the Kruger National Park, eastern Transvaal Lowveld. A total of eight louse species, comprising Amyrsidea desousai, Clayia theresae, Goniodes gigas, Goniodes numidae, Lipeurus numidae, Numidicola antennatus, Numidilipeurus lawrensis and Somaphantus lusius were recovered from the guinea fowls. With the exception of A. desousai, which was not recovered from the guinea fowls in the Bontebok National Park, all eight species were present on the birds at each locality. The prevalence of infestations on the birds at the various localities ranged from 99.2-100%, and the numbers of lice present on individual birds, from 0-3619. Goniodes spp. and N. antennatus were the most abundant and A. desousai the least.

Animals↗

Geomydoecus (Mallophaga: Trichodectidae) from Pappogeomys and Zygogeomys pocket gophers (Rodentia: Geomyidae) in central Mexico.

Descriptions and illustrations are given for 13 previously described species and subspecies of Geomydoecus and four new subspecies: G. mexicanus Price and Emerson (type host: Pappogeomys merriami saccharalis (Nelson and Goldman], G. perotensis perotensis Price and Emerson (type host: P. m. estor (Merriam], G. p. irolonis Price and Emerson (type host: P. m. irolonis (Nelson and Goldman], G. traubi Price and Emerson (type host: P. m. merriami (Thomas], G. fulvescens Price and Emerson (type host: P. m. fulvescens (Merriam], G. coronadoi coronadoi Barrera, n. status (type host: P. m. estor), G. c. submerriami, n. ssp. (type host: P. m. merriami), G. c. saccharalis, n. ssp. (type host: P. m. saccharalis), G. merriami Price and Emerson (type host: P. tylorhinus planiceps (Merriam], G. veracruzensis Price and Emerson (type host: P. m. fulvescens). G. polydentatus polydentatus Price and Emerson, n. status (type host: P. zinseri (Goldman], G. p. angustirostris, n. ssp. (type host: P. t. angustirostris (Merriam], G. mcgregori Price and Emerson (type host: P. fumosus (Merriam], G. wernecki wernecki Price and Emerson, n. status (type host: P. zinseri), G. w. planiceps, n. ssp. (type host: P. t. planiceps), G. alcorni Price and Emerson (type host: P. alcorni Russell), and G. trichopi Price and Emerson (type host: Zygogeomys trichopus trichopus Merriam).

Animals↗

Reduction of adverse drug reactions by computerized drug interaction screening.

Computerized drug-interaction screening systems (CDISS) have been developed as a tool to help decrease the enormous morbidity and expense related to adverse drug interactions. In previous studies the CDISS was used primarily by pharmacists in hospital settings to screen for interactions after the prescription had been written. This study tests the feasibility of family physicians using CDISS before writing the prescription to allow for changes in the prescription while the patient is still in the office. In a 30-day period, 103 patients were screened by family physicians for potential drug-drug, drug-alcohol, and drug-food interactions. Potential drug interactions of varying clinical significance were detected for 71 patients (68.9 percent). The prescription plan was changed for 16 patients (15.5 percent) as a result of using the CDISS. Participating physicians reported that they gained new information in 45.8 percent of the patient encounters, that their awareness of the potential for drug interactions was heightened by participation in this study, and that their exposure to the CDISS was worthwhile as an educational tool. While a few problems, mainly logistic, were noted with the CDISS as used in this study, the authors conclude that with modifications a CDISS can be of great educational and clinical value to the family physician and his or her patients.

Computer Systems↗