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Biomedical subjects

R Cockel

Publications and source records attributed to R Cockel.

At least 37 records · Page 2Linked to original sources
PubMed1982

Gastrointestinal endoscopy services--a review of the 70s with predictions for the 80s.

Information obtained from 3 questionnaires circulated to British gastrointestinal endoscopists has been used to trace the development of endoscopy services during the 1970s. Oesophagogastro-duodenoscopy became available in most hospitals; colonoscopy services were slower to develop and endoscopic retrograde cholangio-pancreatography was performed in under 50% of hospitals. Various therapeutic techniques followed the diagnostic procedures and by the end of the decade constituted one of the major areas of growth. The impact of gastrointestinal endoscopy on other disciplines, diagnostic radiology, surgery, pathology and general practice is reviewed. Organizational aspects of endoscopy services with emphasis on staff, premises, instrumentation and finance are discussed. Analysis of the trends during the 70s has allowed some predictions of the likely developments in the 1980s.

Data Collection↗
PubMed1981

Disinfection in upper-digestive-tract endoscopy in Britain.

A contaminated endoscope may infect patients at upper-gastrointestinal-tract endoscopy (oesophago-gastro-duodenoscopy and endoscopic cholangio-pancreatography) either by the transmission of infection from one patient to another or by inoculation of potentially pathogenic bacteria which have multiplied in the instrument and ancillary equipment during storage. These dangers can be eliminated by careful disinfection with glutaraldehyde, other aldehyde disinfectants, or povidone-iodine. Few centres in Britain are using an effective disinfection procedure and of those who have used glutaraldehyde (the most widely employed) 37% have had serious problems with staff sensitivity. A quick, effective, and safe method for the disinfection of fibreoptic instruments is urgently needed.

Cross Infection↗
PubMed1981

Transient cerebral ischaemic attacks--management and prognosis.

Fifty patients who had recently had a transient ischaemic attack took part in a double-blind cross-over trial of sulphinpyrazone 200 mg 4 times daily against placebo. Each treatment was given for 4 months. The incidence of recurrences was much greater in the initial 4 months but there was no difference between the 2 treatments. A follow-up of 39 of the patients showed that 2 years later 90% of those who had not had a recurrence during the 8 months had suffered no further neurological events whereas of those who did have a recurrence during the study only 47% had no further neurological events.

Aged↗
PubMed1980

Adenocarcinoma of the upper small bowel complicating coeliac disease.

Adenocarcinoma of the small intestine complicating coeliac disease is uncommon. Only 14 cases have been reported, and in only one of these was a jejunal biopsy carried out more than eight months before the diagnosis of malignancy. We describe four more patients with this association, all with long histories of coeliac disease, confirmed in three by jejunal biopsy over five years before the diagnosis of malignancy. Important presenting features of carcinoma were abdominal pain, anaemia, occult gastrointestinal bleeding, abdominal mass, and intestinal obstruction, and these were the main indications for operation. After resection of the tumour survival may be prolonged, as evidenced by one of our cases who remains well eight years after surgery.

Adenocarcinoma↗
PubMed1978

The reasons for failure of endoscopic retrograde cholangio-pancreatography in patients with jaundice.

The results of 100 attempts at endoscopic retrograde cholangio-pancreatography (ERCP) performed in patients with jaundice have been reviewed. The examination provided a diagnosis in 75% of cases. The reason for failure to cannulate the correct duct was obstruction at the lower end of the common bile duct in 15 patients and distortion of the duodenum in seven. There was no cause for the failure in only two patients. Even with a perfect technique it will not always be possible to obtain an endoscopic cholangiogram. However, as the commonest cause of failure is obstruction, transhepatic cholangiography should usually succeed when ERCP fails.

Adult↗
PubMed1977

Clinical picture of peptic ulceration diagnosed endoscopically.

Clinical features and laboratory data are presented for 100 patients with benign gastric ulceration and 150 patients with duodenal ulceration confirmed endoscopically in a district general hospital unit. Abdominal pain was the commonest indication for endoscopy, but one third of examinations were performed for acute gastrointestinal haemorrhage. Although the patients were selected by referral for endoscopy their clinical presentation, age, and sex distribution were similar to those reported in previous general surveys. There were no clinical features which clearly distinguished gastric from duodenal ulceration. However, of those with gastric ulceration younger patients more often had distal ulcers and presented with pain, while elderly subjects tended to have high lesser curve involvement and presented with haemorrhage. Moreover, all females presenting with haemorrhage were aged over 50 years, while 6% of males bleeding from gastric ulceration and 40% of males bleeding from duodenal ulceration were under this age. Anaemia when present, except in two premenopausal females, indicated either a recent acute gastrointestinal haemorrhage or a coexistent second diagnosis.

Adolescent↗
PubMed1973

Gastric photography.

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Fiber Optic Technology↗