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Biomedical subjects

R Carlisle

Publications and source records attributed to R Carlisle.

51 records · Page 3Linked to original sources

Premature valve closure in patients with a mitral Starr-Edwards prosthesis and aortic incompetence.

A mitral Starr-Edwards ball valve has, in three patients with concomitant aortic incompetence, permitted recognition of intermittent premature valve closure by auscultation and this has been documented by phonocardiograms. In two instances the observations were confirmed during cardiac catheterization. The features of premature Starr valve closure are described and the mechanism is discussed.

Aortic Valve↗

Incidence of stroke in an African City: results from the Stroke Registry at Ibadan, Nigeria, 1973-1975.

Studies based on hospital populations reported from negro communities in several countries in Africa suggest that cerebrovascular disease (CBVD) shows increasing mortality and morbidity in Africans although 2 decades ago CBVD was believed to be uncommon. We report the first study in the African to determine the incidence of stroke in an urban area, Ibadan, Nigeria.

Adolescent↗

How important a priority is travel medicine for a typical British family practice?

BACKGROUND: Primary care teams have to supply travel health advice to increasing numbers of long haul travelers but there is a shortage of information derived from general practice settings about the risks patients are exposed to. We aimed to determine the numbers of our patients visiting high-risk destinations, to see if they reported complying with health advice, and whether or not they became ill. METHODS: We performed a retrospective study in a typical British, town center, family practice in Mansfield, Nottinghamshire. A postal questionnaire survey was sent to 200 adults, aged between 16 and 76, randomly selected from the practice register, and 351 adults who had attended the practice travel clinic over a 1-year period between 1997-1998. RESULTS: Responses were received from 84% of the random sample and 86% of the travel clinic group. Out of 11,000 patients registered with the practice, we identified 187 patients who had traveled to high-risk destinations such as Africa, Asia, South America or the Caribbean. The majority of these had attended the practice travel clinic. Despite this, 41% became ill (mainly diarrhea), 10% were sufficiently ill to be confined to bed. Fifty-nine percent of patients who required malaria chemoprophylaxis reported they had not complied fully with advice given. Reported illness rates for medium and low risk destinations were 27 and 19% respectively. CONCLUSIONS: The results suggest that giving health advice to long haul travelers should be an important priority for primary care teams. Travelers have a high episode rate of illness and put themselves at risk of acquiring malaria. Most travelers to high-risk destinations do attend the travel clinic for health advice but compliance with that advice is poor. People traveling to lower risk destinations still experience an appreciable rate of illness and are less likely to be seen in the travel clinic.

Adult↗

Pulse upstroke in Africans.

Electro-acoustic time intervals are measured on sphygmorecordings from the QRS to the Korotkoff sound. Simultaneously recorded brachial cuff pressures plotted against the interval for each beat constitute a sphygmochronogram. For a series of 56 individuals free of cardio-respiratory disease who presented at University College Hospital, Ibadan, the parameters of the sphygmochronogram showed expected intercorrelation but there was an unexpectedly short ti (electro-acoustic time interval at the inflection) of 0.16 + 0.02s, compared with 0.21 + 0.02s for series in the U.S.A. and Portugal. Values for dP/dt init. (rate of pressure rise in early ejection) were not reported for these series but our results are similar to those from Sweden.

Adolescent↗