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Biomedical subjects

R C Goodlin

Publications and source records attributed to R C Goodlin.

At least 181 records · Page 10Linked to original sources

Naloxone and its possible relationship to fetal endorphin levels and fetal distress.

This case report of fetal asphyxia and related studies suggest that fetal endorphins play a role in fetal pain tolerance and cardiovascular asphyctic responses. Elevated fetal endorphin levels may, like narcotics, produce abnormally "flat" fetal heart rate patterns intrapartum and fetal tolerance to pain. Although naloxone hydrochloride was used with some success to return flat fetal heart rate patterns to "normal," the unopposed antagonism of fetal endorphins by naloxone in times of fetal distress may be detrimental.

Adult↗

Impending gestosis.

Five cases of pregnant woman with symptoms of right upper quadrant pain, hemoconcentration, liver dysfunction, and thrombocytopenia are presented as representative of impending gestosis. Plasma volume expansion achieved by either bed rest or intravenous albumin administration appeared to be effective therapy. It is presumed that impending gestosis represents an early form of severe toxemia (edema/proteinuria/hypertension [EPH[ gestosis).

Adolescent↗

Low-risk obstetric care for low-risk mothers.

The perinatal and maternal complication rates of 500 births in an alternate birth centre (ABC) were compared with a similar number of apparently low-risk pregnancies cared for in standard labour and delivery rooms. For babies the complication rates were higher for those born in the delivery room, but for mothers the rates were higher for those in the ABC. Because of the apparently low incidence of complications among babies delivered in the ABC it may be safe and perhaps preferable not to use electronic fetal monitoring in truly low-risk gravidae. A safe ABC programme, however, requires rigid adherence to protocols by both the mother and centre staff.

California↗

Extraperitoneal cesarean section revisited.

A retrospective analysis was made of 186 consecutive primary cesarean sections performed on patients at high risk for infection to determine whether extraperitoneal cesarean section would have decreased the incidence of infections and other complications. Women who theoretically would have benefited most from extraperitoneal cesarean section were not candidates for the procedure because of technical reasons, while those who would have been candidates for the procedure did very well despite the fact that the procedure was not done. Except for somen with severe toxemia, prophylactic antibiotics markedly reduced febrile morbidity. A number of significant unsuspected pathologic conditions also would not have been diagnosed if the extraperitoneal cesarean section technique had been used. It is concluded that prophylactic antibiotics and intraperitoneal cesarean sections are the preferred techniques even for those women with apparent amnionitis.

Anti-Bacterial Agents↗

Delivery of the tiny newborn.

Obstetric factors related to the survival of 100 newborn infants weighing between 800 and 1,350 grams were analyzed. Available data suggest that maternal intrapartum antibiotic and steroid administration and delivery by classical cesarean section are associated with increased newborn survival.

Anti-Bacterial Agents↗

A homestyle delivery program in a university hospital.

The Homestyle Delivery Program, an alternative birth service at the University of California Davis Medical Center, Sacramento, is presented. The program was developed jointly by the departments of family practice, obstetrics, and pediatrics, in response to the needs and desires of patients and physicians to participate in a more natural family centered birthing process. A brief description of the program and data from the first 1 1/2 years of operation is given. This program, in contrast to many other alternative birthing programs, involves physicians in training; that is, residents in family practice and obstetrics who are being taught during their obstetrical training how to create and facilitate an intimate family oriented home-like birthing. Satisfaction with the program on the part of the participating families as well as physicians and program staff has been very high. Today, more families in this society are demanding this kind of alternative birthing experience; the Homestyle Delivery Program meets their needs and to data has demonstrated no increased risk to mother or infant.

California↗

Cervical incompetence, hourglass membranes, and amniocentesis.

A method is described for treatment of cervical incompetence when there are bulging fetal membranes (hourglassing). The technique consists of abdominal amniocentesis and amniotic injection of antibiotics prior to closing the cervical defect.

Amniocentesis↗