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Biomedical subjects

R C Benson

Publications and source records attributed to R C Benson.

At least 73 records · Page 4Linked to original sources
PubMed1985

The etiology and treatment of delayed bleeding following percutaneous lithotripsy.

In 1,032 percutaneous stone manipulations the incidence of significant, documented or presumed vascular injuries was 0.9 per cent. Seven cases of pseudoaneurysm, arteriovenous fistula or vascular lacerations were found, all of which were diagnosed angiographically. The patients were treated successfully with transcatheter embolization techniques. Two additional patients experienced delayed bleeding, presumably from vascular injuries, which resolved spontaneously with conservative therapy. Arteriography should be performed in these patients with serious postoperative bleeding. Embolization of the peripheral vessel is preferable to flank exploration.

Aged↗
PubMed1985

Pelvic lymphadenectomy and radical cystectomy for transitional cell carcinoma of the bladder with pelvic nodal disease.

Past and present methods of treatment for patients with stage D1 (T1-4 N+ MO) transitional cell cancer of the urinary bladder have proved to be largely ineffective. This report on 57 patients with stage D1 disease confirms this impression and demonstrates that radical operation alone is associated with a 5-year survival rate of only 10%. Survival is related to tumour grade and to the number of pelvic lymph nodes involved; furthermore, complete lymphadenectomy may contribute to improved patient survival. Effective treatment programmes for stage D1 bladder cancer are lacking and efforts should be directed toward developing treatment protocols that combine radical cystectomy and meticulous pelvic node dissection with an effective adjuvant systemic treatment programme.

Adult↗
PubMed1985

Colon perforation following percutaneous nephrostomy and renal calculus removal.

Two patients had colonic perforation as a result of percutaneous nephrostomy placement followed by track dilatation and renal calculus removal. We present the technical aspects of nephrostomy placement and stone removal, as well as the clinical diagnosis and management of these cases. Both patients recovered well with conservative therapy and required no surgical intervention. This report reviews the anatomic considerations for percutaneous nephrostomy in patients undergoing renal stone removal.

Adult↗
PubMed1985

An updated approach to correcting impotence in elderly men.

A myth about transurethral prostatectomy is that it renders the patient unable to achieve an erection. There is no evidence that this is so, nor any evidence that prostatic hypertrophy itself causes impotence. It is imperative that the patient understand what the prosthesis will and will not do for him. All currently available devices provide a penile shaft rigid enough for intromission, but because all devices occupy only the corpora cavernosa, the erect penis will not be as long or as great in circumference as the patient's physiologic erections once were.

Aged↗
PubMed1984

Bilateral pelvic lymphadenectomy and radical retropubic prostatectomy for Stage C adenocarcinoma of prostate.

A series of 105 patients with surgical Stage C adenocarcinoma of the prostate underwent pelvic lymphadenectomy and radical retropubic prostatectomy and were followed up from one and one-half to fifteen years; 33 (31%) of the 105 had clinical Stage C disease. Of the 105 patients, 92 were at risk for greater than or equal to two years, 42 for greater than or equal to five years, and 12 for greater than or equal to ten years. Survival and disease progression were related to tumor grade (Mayo grades 1 through 4) and tumor bulk (less than 3, 3 to 10, greater than 10 cm3) but not to seminal vesicle involvement. Twenty-seven patients received adjuvant treatment (orchiectomy, DES, radiation, or combinations of these); it was administered to patients with higher tumor grades, larger tumor bulk, and/or residual cancer. Overall actuarial survival at five and ten years was 85 per cent and 72 per cent, respectively; five-year nonprogression rate was 64 per cent. Local recurrence was noted in only 8 patients (7.6%). Radical surgical treatment for nonbulky Stage C disease of the prostate is associated with favorable survival results and good local control. Adjuvant treatment may favorably affect disease outcome. Clinical seminal vesicle involvement with negative urethrocystoscopy should not necessarily deter the surgeon from planning radical prostatectomy. Prospective adjuvant treatment protocols need to be developed to identify the value of adjuvant hormone and/or radiation therapy.

Adenocarcinoma↗
PubMed1984

Cancer-to-cancer metastasis.

The development of another separate primary cancer in a patient with 1 malignant tumor is not uncommon but metastasis of a malignant donor tumor to a different host tumor is extremely rare. Most recipient tumors have been primary renal cell carcinomas. We report a case of metastasis of a malignant melanoma to a renal cell carcinoma.

Adenocarcinoma↗
PubMed1984

Carcinoma of the seminal vesicle.

Strict criteria were applied to 12 cases of carcinoma of the seminal vesicle in the Mayo Clinic tumor registry. Diagnosis was carcinoma of the seminal vesicle if the neoplasm was a papillary or anaplastic carcinoma localized primarily to the seminal vesicle and no other primary tumors were demonstrated. In addition, some degree of mucin production was required, especially when prostatic involvement was present. Only 2 of our cases and 35 cases reported previously were judged acceptable or probable cases of carcinoma of the seminal vesicle. Prognosis for patients with this tumor is poor. A combination of extirpative surgery and hormonal therapy appears to provide the best opportunity for extended survival, although this remains to be proved.

Adenocarcinoma↗
PubMed1984

Endoscopic evaluation and treatment of patients with idiopathic gross hematuria.

We evaluated 4 patients with long-standing unilateral essential gross hematuria by newer endourological techniques. All 4 patients underwent ureterorenoscopy and 3 underwent percutaneous nephroscopy. Nephroscopy identified a bleeding site in 3 patients and ureteroscopy in 1. The bleeding sites were fulgurated and the hematuria has not recurred during followup. Percutaneous nephroscopy and/or ureterorenoscopy should be considered in selected patients with unilateral essential gross hematuria.

Adult↗
PubMed1984

Relationship of leukoplakia to urothelial malignancy.

The records of 108 patients presenting with leukoplakia of the urinary tract during the last 35 years were reviewed to define the natural history of this disease, with emphasis upon its association with urothelial cancer. Of the 108 patients 24 had upper urinary tract, 78 bladder and 10 urethral leukoplakia (1 with renal and bladder involvement, 3 with bladder and urethral involvement, and 1 with ureteral and renal involvement). Presenting complaints were primarily irritative. To date, 41 patients (37 per cent) have had associated carcinoma of the urothelium: 23 (21 per cent) presented with a concomitant or previous carcinoma and 18 of 85 (21 per cent) presenting without a concomitant or previous neoplasm have had documented progression to cancer. These figures support the concept that leukoplakia is a premalignant disease and that patients with this diagnosis deserve careful and frequent followup.

Aged↗
PubMed1984

Long-term evaluation of the inflatable penile prosthesis.

An in-depth evaluation of 88 patients who received inflatable penile prostheses generated survival plots for the prosthesis as a total unit and for each of the component parts. A plot of the prosthesis survival for first implantation revealed that 50 per cent survived 2.5 years without failure. Cylinder malfunction was responsible for the greatest decrease in prosthesis life expectancy.

Equipment Failure↗
PubMed1984

Bilateral pelvic lymphadenectomy and radical retropubic prostatectomy for adenocarcinoma confined to the prostate.

A total of 519 patients with clinical stage B disease underwent radical prostatectomy from 1966 to 1981: 65 (12.5 per cent) had pathologic stage D1, 72 (14.0 per cent) pathologic stage C and 382 (73.5 per cent) pathologic stage B disease. Of the 519 patients 320 with pathologic stage B1 (239) or B2 (81) adenocarcinoma of the prostate and no prior hormonal or radiation therapy underwent complete pelvic lymphadenectomy and radical retropubic prostatectomy. Stage, grade and size of tumor were associated significantly with interval to disease progression but not with survival. The probable explanation for this observation is that only 2 per cent of 186 patients who were followed for 5 years and 2 per cent of 46 who were followed for 10 years died of prostatic carcinoma within these intervals. The over-all survival of patients who had intracapsular prostatic carcinoma was not different from that of an age-matched surgical control group (men undergoing total hip arthroplasty during the same interval). These observations suggest that although morbidity from alternative therapies may vary no other treatment modality offers survival superior to that observed for pelvic lymphadenectomy and radical retropubic prostatectomy in patients with pathologic intracapsular prostatic cancer.

Adenocarcinoma↗
PubMed1984

Cryptorchism and maternal estrogen exposure.

A case-control study of in utero estrogen exposure and cryptorchism was carried out using as cases males born in Rochester, Minnesota, during the years 1943-1973 who were diagnosed as having cryptorchism. Two different control groups were selected for comparison, control group I being more closely matched than control group II. The estimated relative risks (RR) for estrogen exposure were 1.3 (95% confidence interval (CI) = 0.5-3.1) and 1.1 (95% CI = 0.5-2.6) for control groups I and II, respectively. In the univariate analysis, the only significantly elevated relative risks found were those for bleeding and spotting in the third trimester for cases versus control group II (RR = 3.7; 95% CI = 1.1-15.7), birth weight less than 2,500 g for cases versus control group II (RR = 3.4; 95% CI = 1.3-9.9), and gestational age of 40 weeks or less for cases versus control group I (RR = 1.8; 95% CI = 1.2-2.9). No elevated relative risks were associated with other problems during the index pregnancy or with prior pregnancies, nor with progestin exposure, smoking, presentation at delivery, or mode of onset of labor. Multivariate analysis also provided no evidence to suggest that in utero estrogen exposure is associated with cryptorchism in male offspring.

Adult↗
PubMed1984

Endoscopic management of bladder cancer with hematoporphyrin derivative phototherapy.

The propensity of hematoporphyrin derivative (HpD) to fluoresce in the red portion of the spectrum when exposed to near-ultraviolet light has enabled investigators to substantiate that HpD selectively localizes in dysplastic and neoplastic urothelial cells. More important from a clinical standpoint is the cytotoxicity that occurs when cells that have absorbed HpD are exposed to light of wavelengths that correspond to its absorption bands. Several early clinical studies have substantiated the potential clinical usefulness of HpD phototherapy.

Carcinoma in Situ↗