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Biomedical subjects

R C Anderson

Publications and source records attributed to R C Anderson.

At least 163 records · Page 9Linked to original sources

Electrophoretic analysis of Antarctic fish from South Georgia.

White muscle samples of Antarctic fish (Notothenia rossii, N. neglecta, N. gibberifrons and Chaenocephalus aceratus) were subjected to electrophoretic tests. Isoelectric focusing of general muscle proteins provides a quick method of identifying species. Six muscle enzymes were resolved by horizontal starch gel electrophoresis. These are presumed to be the products of ten independent gene loci. Coefficients of genetic distance were calculated and substantially agree with the conventional taxonomy. Levels of genetic variability are within the normal range for marine teleosts. Two polymorphic enzymes. GPI and PGM, might prove useful as 'genetic tags' for stock identification.

Animals↗

Observations on Turgida turgida (Rudolphi, 1819) (Nematoda: Physalopteroidea) in the American opossum (Didelphis virginiana).

Turgida turgida is a common parasite of the stomach of the American opossum in Florida. Worms were usually found attached to the greater curvature of the corpus of the stomach. Ulcers always occurred at the site of the attachment. Large ulcers were associated with groups of adult parasites and were found in the oldest experimental infections. Turgida turgida fed on food within the stomach of the opossum and attached to the stomach wall when not feeding. Third-and fourth-stage larvae were found in opossums in Florida mainly from May to August suggesting that this is a major period of transmission.

Animal Population Groups↗

Occult filariasis in crows (Corvus brachyrhynchos brachyrhynchos Brehm) infected with Splendidofilaria caperata Hibler, 1964 (Nematoda: Filarioidea).

Adult Splendidofilaria caperata Hibler, 1964 were found in the tunica media of the pulmonary arteries of 21% of 341 crows (Corvus brachyrhynchos brachyrhynchos Brehm) wintering in southern Ontario, Canada. Microfilariae of S. caperata were not observed in the peripheral blood or in skin snips of infected crows. Microfilariae were rarely found in lung blood and then only in small numbers. Microfilariae were apparently overcome in the wall of the pulmonary artery; chronic inflammation was associated with their presence in arterial tissue. Crows apparently acquire S. caperata from insects that hae fed on birds in which a microfilaraemia does develop.

Animals↗

Development of Pelodera strongyloides (Schneider, 1860) Schneider, 1866 (Nematoda: Rhabditidae) in culture.

Dauerlarvae of Pelodera strongyloides, recovered from two species of lemmings, Dicrostonyx groenlandicus (Traill) and Lemmus trimucronatus (Richardson) trapped at Eskimo Point, N.W.T, were cultured on agar medium with E. coli. Development from egg to adult stage was followed. Eggs hatched between 22 and 26 hours at 22 degrees C. The first moult occurred 24 to 28 hours after the eggs hatched, the second at 40 to 48 hours, the third at 60 to 64 hours and the fourth at 84 to 88 hours at 22 degrees C. Adults lived approximately 5 to 6 days and females oviposited for 2 to 3 days during this time. All stages were measured and described. The effect of temperature on development was examined. Dauerlarvae survived freezing temperatures, short periods of desiccation and prolonged periods without food.

Animals↗

Diplotriaena tricuspis (Fedtschenko, 1874) (Nematoda: Diplotriaenoidea) in crows (Corvus brachyrhynchos Brehm) wintering in Ontario.

Two hundred and eleven of 4404 (4.8%) crows (Corvus brachyrhynchos) collected in the winters of 1976-77 and 1977-78 in Essex County, southwestern Ontario, were infected with Diplotriaena tricuspis (Fedtschenko, 1874) Henry and Ozoux, 1909. Prevalence of potentially patent infections was only 2.6%, however, as crows often had nematodes of a single sex only. Intensity was 4.0 (1-74) and was similar in both male and female crows of all age groups. Intensity tended to be higher in young-of-the-year crows than yearlings and adults.

Animals↗

Procyonostrongylus muelleri gen. et sp. n. (Metastrongyloidea: Angiostrongylidae) from the raccoon (Procyon l. lotor).

Procyonostrongylus muelleri gen. et sp. n. from under the epithelium of the epiglottis of Procyon l. lotor is distinguished by 1) the absence of lips; 2) a highly developed reinforced bursa with a deep terminal incision; 3) highly developed toothlike dorsal rays; 1) greatly reduced externodorsal rays; and 5) the terminal or subterminal anus and vulva in the female.

Animals↗

Hepatic uptake of propranolol.

Isolated rat livers were perfused with propranolol and other drugs in a simplified recirculation system without plasma proteins or erythrocytes. The propranolol levels in the reservoir declined biphasically. The first phase was rapid and almost flow-limited despite use of high perfusion flow rates. This rapid uptake generated liver/perfusate ratios greater than 25 and was not significantly diminished by lowering the temperature or removing oxygen from the system. It appeared to reflect one or more physical binding processes. Autoradiography showed high concentrations of propranolol in the periportal zones of the liver lobule. The second, slower phase of uptake was associated with metabolism of propranolol to other compounds and was temperature, oxygen and concentration dependent. A number of drugs inhibited the slow phase but had little effect on the rapid uptake phase. Several of these drugs were able to displace small amounts of propranolol from the liver.

Animals↗