Norway rat haemoglobin phenotypes: which is the original?
On the basis of the incidence of haemoglobin alleles in different populations of rats, the hypothesis is discussed that the HbbB is phylogenetically "older".
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Publications and source records attributed to R Brdicka.
On the basis of the incidence of haemoglobin alleles in different populations of rats, the hypothesis is discussed that the HbbB is phylogenetically "older".
We examined 6-PGD isozyme patterns in laboratory rats (Rattus norvegicus) and found the phenotype S in the lines CAP/Cub, WAG/RijCub, BDV/Cub, BDVII/Cub, BDX/Cub, and the phenotype F in the lines LEP/Cub, DA/Cub, AVNj/Cub.
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We made use of the genetic polymorphism of haemoglobin in the laboratory rat and developed a congenic strain LEW.Hb A differing from the original LEW strain in the type of haemoglobin. The exclusion of the histoincompatibility reactions allows a long-term follow-up of the bone marrow transplants on the basis of changes in the haemoglobin pattern.
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