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R Bouvier

Publications and source records attributed to R Bouvier.

At least 145 records · Page 8Linked to original sources
PubMed1989

[Ulcero-necrotizing enterocolitis: the role of cytomegalovirus. Apropos of a case].

The authors report a case of Wilson-Mikity syndrome in a preterm newborn, that was followed on the 28th day of life by a necrotizing enterocolitis with colic stenosis. The finding of cytomegalic cells on the pathologic examination of the intestinal lesions, the presence of the virus on direct examination of a tissue sample, the elevated IgG levels and the presence of IgM demonstrated a cytomegalovirus infection. The authors discuss the role of this virus in the pathogenesis of the affection, either as directly responsible for the enterocolitis or as a secondary colonization of previous lesions.

Colectomy↗
PubMed1989

[Familial infantile nephrotic syndrome with ocular abnormalities].

Two siblings born from consanguineous parents experienced infantile nephrotic syndrome with ocular and neurological abnormalities and a micropenis in the boy; both patients died before age 1. The opportunity to perform successively a renal biopsy and a two-step binephrectomy permitted a good histological follow-up. The lesions were characterized by mesangial involvement, followed by an extensive extracapillary proliferation and tubular dilatations with a high mitotic activity of the epithelium with anisocaryosis; the main features consisted in major ultrastructural changes of the glomerular basement membrane which were more significant and different from those previously described in the diffuse mesangial sclerosis. These 2 cases may either constitute a new entity or an extreme form of diffuse mesangial sclerosis, supported by recessive autosomal inheritance.

Basement Membrane↗
PubMed1988

[Renal tumors in children, excluding Wilms' tumor. Apropos of 29 cases].

The authors present a multisource study of 29 kidneys tumors (Wilms excepted) in children. The most common types (18 cases) are tumors from metanephrogen blastema (congenital mesoblastic nephroma, nephroblastomatosis and nodular renal blastema, multilocular cystic nephromas. Mature kidney tumors are much more rare in childhood (8 cases): they are epithelial tumors (adenoma or adenocarcinoma) or mesenchymal neoplasms. In one case, histological study don't permit to list a malignant tumor to one of previous categories. Finely, among secondary tumors, two localisations of hemopathy are reported. After a limited exposure of cases and review of the literatures the authors emphasize the anatomo-clinical aspects, the value of paraclinical exams and the treatment of each type of tumor.

Female↗
PubMed1988

[Transient dilatation of the intra- and extra-hepatic bile ducts. A new aspect of bile duct involvement in scarlet fever].

An extra- and intra-hepatic bile duct dilatation has been observed in a child in the course of scarlet fever. Manifestations of cholestasis, cytolysis and inflammation were present. Pruritus disappeared within 2 months, biological abnormalities within 3 months and ultrasonic bile duct abnormalities between 3 and 6 months, with a follow-up of 9 months. This case report suggests a relationship between a transitory obstruction, possibly toxic in origin, of the bile ducts and the scarlet fever.

Bile Ducts, Intrahepatic↗
PubMed1987

Ontogeny of somatostatin-like immunoreactivity in the human fetus and infant spinal cord.

The localization and distribution of somatostatin like-immunoreactivity (SSLI) in postmortem human fetus and infant spinal cord and dorsal root ganglia were studied by using the indirect immunofluorescence technique. SSLI, which was mostly located within varicose fibers and terminal-like structures, occasionally within cell bodies, was detected during early fetal life (on gestational week 9 and beyond). The changes occurring from the early to the late fetal and infant stages mainly resulted in a progressive increase in the number of somatostatin-like immunoreactive fibers within most of the gray areas. On the whole the majority of immunolabelled fibers and terminal-like structures were observed over the superficial layers of the dorsal gray including the marginal zone and the substantia gelatinosa. Other regions displaying a moderate number of somatostatin-like immunoreactive fibers were the intermediate gray and the gray commissure area around the central canal. A few scattered immunofluorescent fibers were unevenly distributed over the white matter especially in the lateral and ventral funiculus areas and near the ventral motor nuclei. A few somatostatin-like immunoreactive cell bodies were occasionally found in the superficial layers of the dorsal gray and in the intermediolateral gray. Immunolabelled cells were further usually visualized in dorsal root ganglia. Although the distribution patterns of somatostatin-like immunoreactive structures were similar throughout the entire spinal cord, the highest density of immunolabeled fibers, however, was seen at the lumbosacral level. Our results indicate that in the human spinal cord SSLI is already widespread before birth. It is further suggested that somatostatin ontogenesis in human spinal cord and dorsal root ganglia begins early in fetal life.

Embryo, Mammalian↗
PubMed1987

[Benign tumors of the posterior urethra in children. Apropos of an unusual case of rhabdomyoma of fetal type].

The authors report a very unusual case of urethral tumor in a child: fetal rhabdomyoma, after nephroblastoma treated by enlarged nephrectomy. Excellent result is observed four years after endoscopic treatment of this prostatic urethral tumor. Clinical and histological features of posterior urethral tumors and rhabdomyoma are recalled; the association nephroblastoma-tumor of urethra is discussed.

Humans↗
PubMed1987

[Permanent constriction of the jaws due to progressive ossifying myositis].

A case is reported of progressive ossifying myositis (fibrodysplasia ossificans progressiva, Münchmeyer's disease) with onset at 16 years of age by a lesion of internal pterygoid with limitation of opening of mouth. Surgery to relieve ankylosis was followed by recurrence. Diagnosis was established only after the appearance of lesions in other regions (sternocleidomastoid, latissimus dorsi, lumbar muscles...). Clinical and paraclinical signs of this exceptionally rare disease are reviewed and diagnostic difficulties at onset of the disease discussed. Treatment of acute myositis episodes with diphosphonates delays passage to the ossification stage, allowing local surgery to be performed with less risk of relapse.

Adolescent↗
PubMed1987

[Extensive congenital stenosis of the bulbo-membranous urethra in a child. Apropos of a case discovered in a newborn infant].

A congenital atresia of the bulbo-membranous urethra had been reported. The atresia extended for 1.5 cm. It presented early in the neonatal period with major dilatation of the upper urinary tracts. After a preliminary urinary diversion, the surgical repair through the perineum was done at the age of 18 months. Such cases are not seen frequently. This atresia must be differentiated from posterior urethral valves type III, and from other stenoses either iatrogenic, traumatic, or inflammatory. The partial atresia is the only type compatible with life. It may be presented in two forms: annular constriction or extended stenosis. The mechanism of evolution is not very clear: it is either due to a bad resorption of the urogenital membrane or a defect in the embryogenesis of the urethral tube. Treatment differs according to the site and extent of the lesion simple dilatation, internal urethrotomy, or urethroplasty in one or several stages can be done.

Humans↗
PubMed1986

Metastatic interstitial pneumonitis after autologous bone marrow transplantation. A consequence of reinjection of malignant cells?

Two cases of fatal interstitial pneumonitis developing after an autologous bone marrow transplantation are described. In both cases the autopsy revealed diffuse malignant pulmonary involvement. The first case involved a 4-year-old boy who had a Burkitt's lymphoma; the second case involved a 4-year-old girl with a neuroblastoma. The authors postulate that in these cases, the clinical picture may have been related to reinfusion of malignant cells.

Abdominal Neoplasms↗
PubMed1986

[Fulminant herpesvirus hepatitis in a child. Apropos of 2 cases].

The authors report two cases of fulminant hepatitis in children. Coagulopathy was early demonstrated in the two patients. The illness progressed rapidly and the two children died before receiving antiviral treatment. Herpes virus was demonstrated in the hepatocytes by electron microscopy.

Blood Coagulation Disorders↗
PubMed1986

[Study of the DNA content of 72 cases of bladder tumors using flow cytometry. Relation with anatomoclinical data].

The DNA content of 72 bladder tumors and 20 healthy bladders was studied with flow cytometry. Reproducibility of DNA measurement was systematically verified with the use of 3 controls: calf thymocytes, mouse hepatocytes and a mixture of human lymphocytes with trout red blood cells. For each tumor or normal bladder, a first sample containing urothelial cells only and a second sample with the addition of trout red blood cells were systematically examined. In the first group of patients with healthy bladders the percentage of urothelial cells with a DNA content greater than G0 G1 (2N) was on average 7.9% +/- 2.8%. Among the second group of 72 tumors, 2 DNA profiles were remarkable: in a first group (39/72; 55%) DNA profile was unimodal (single diploid peak); in a second group (33/72; 45%) DNA profile was bimodal (association of a diploid peak with an aneuploid one). Comparison of flow data with pathology data (WHO classification) clearly demonstrated that the presence of an aneuploid peak, characterizes grade elevation and infiltration. Hence, 1/16 (6%) of grade I; 7/75 (28%) of grade II; 25/31 (81%) of grade III tumors show an aneuploid peak, as well as 11/44 (25%) of Ta; 9/14 (64%) of T1; 5/6 (83%) of T2, and 8/8 (100%) of T3 tumors. Demonstration of an aneuploid peak with flow cytometry particularly in the group of patients having non infiltrating Ta tumors (11/44 in our series) could further either lead to a closer follow-up of this high risk group of patients or to the early recommendation of a non conservative treatment.

DNA, Neoplasm↗
PubMed1985

Clinically occult bladder cancer diagnosis. Trial using ultraviolet cystoscopy.

Ultraviolet cystoscopy was used to demonstrate flat cancerous and precancerous bladder lesions by two techniques based on different principles: the loss of epithelium blood group antigenic expression using immunofluorescence reaction, and submucosa neoangiogenesis after fluorescein intravenous injection. The results obtained with these two techniques were disappointing, but do not preclude the use of ultraviolet cystoscopy in this type of study.

ABO Blood-Group System↗
PubMed1984

Bronchial carcinoid with fibrillary inclusions related to cytokeratins: an immunohistochemical and ultrastructural study with subsequent investigation of 12 foregut APUDomas.

A bronchial P cell carcinoid, which was negative for all hormones immunocyto chemically tested, showed a globular intracytoplasmic inclusion in almost every cell. The inclusions were not clearly distinguishable using the haematoxylin- eosin- safran procedure; they were best demonstrated with the Masson trichrome stain and the Grimelius technique and were easily detected in 1 micron thick Epon sections as target-like structures. On electron microscopy, they were found to be composed of filamentous aggregates entrapping a few endosecretory granules, which showed degenerative changes. The filaments, 8-10 nm in diameter, lacked any periodicity; they were randomly dispersed in the central area and arranged in broken concentric swirls at the periphery of the inclusions. The globules lacked the tinctorial properties of amyloid, but showed a strong immunostaining for keratin-like proteins. A systematic investigation of 12 APUDomas of bronchial or duodenopancreatic origin, using both light and electron microscopy, identified a few filamentous bodies in one case, a somatostatin cell tumour of ampulla of Vater. In both cases, the structures appeared similar to those previously reported in growth hormone cell pituitary adenomas as well as in a few bronchial or gut carcinoids. Whatever their nature, morphological data suggest that they are related to abnormalities in the secretory function, involving the Golgi apparatus, the endosecretory granules and the microtubular microfilamentous system.

Adult↗