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Biomedical subjects

R Berndt

Publications and source records attributed to R Berndt.

At least 37 records · Page 2Linked to original sources
PubMed1995

Endometrioid adenoma (polypoid endometriosis) of the omentum maius.

Endometrioid adenoma (polypoid endometriosis) of the omentum maius in an 89-year old female is reported. The tumor measured 1 cm in diameter and consisted of resting or weakly proliferating, partially macrocystic endometrial glands, encapsulated by delicate fibrous connective tissue. Immunohistochemically, glandular and stromal cells expressed estrogen receptor strongly, progesterone receptor weakly and CA 125 only weakly in a few glands. This is another, but rare example of the capacity of the omentum maius to develop tumors of the Müllerian variety.

Abdominal Neoplasms↗
PubMed1994

[Comparison of computerized tomography and B-image ultrasound in imaging diagnosis of the mediastinum].

40 patients with suspected mediastinal tumors were independently examined with computed tomography (CT) and sonography. The findings were confirmed by bronchoscopy, mediastinoscopy or surgery. In the assessment of the upper and middle mediastinum, sonography reaches a high sensitivity. On the contrary, in the evaluation of the anterior and posterior mediastinum, sonography is clearly inferior to CT. 90% of the tumors demonstrated by CT could be assessed with sonography. The most frequent tumors can be diagnosed with ultrasound. The evaluation of tumors in the paravertebral and retrosternal space is limited. Sonography of the mediastinum is a noninvasive, well-reproducible and cost-effective imaging modality that provides important information in cases of unclear X-ray and CT findings. The preliminary results encourage to a more frequent use of mediastinal sonography.

Adult↗
PubMed1991

Differential basement membrane composition in multiple epithelioid haemangioendotheliomas of liver and lung.

We report a case of epithelioid haemangioendothelioma involving both lung and liver. The tumour cells were positive for factor-VIII-related antigen. Immunohistochemical analysis of various basement membrane components in tumour tissue of lung and liver showed striking differences. In the liver tumour there was selective expression of collagen IV, with minimal and focal amounts of laminin and basement membrane-associated heparan sulphate proteoglycan. In the lung tumour nodules, in contrast, all these basement membrane components were present. These patterns of basement membrane expression closely resemble those of normal liver and lung basement membrane respectively. We suggest that this provides evidence that epithelioid haemangioendothelioma arises from local endothelial cell proliferation and that it supports the assumption of a multicentric rather than metastatic origin when multiple tumour deposits are found.

Aged↗
PubMed1990

Screening for lung cancer in the middle-aged.

A screening programme for lung diseases has been in operation in the German Democratic Republic for more than 3 decades. The programme is based on biennial chest X-rays (70 x 70 mm posterior-anterior) of the population 40 years of age or over. With respect to lung cancer the results show that, for the population under 60 years of age, the adjusted relative risk of dying from lung cancer among subjects who took part in the last screening round compared with subjects who did not but were screened at least once during the preceding 10-year period was 0.93 (95% confidence interval 0.65-1.33).

Age Factors↗
PubMed1989

Creatine-kinase-BB after severe head-injury as an index of prognosis in relation to nature of trauma and patients age.

Creatine-Kinase-BB (CK-BB) is a brain specific enzyme, with a prognostic value for the patient's outcome after head-injury. We have investigated 76 brain injured patients and attempted to show a correlation of the concentrations of CK-BB and the Glasgow-Outcome-Scale (GOS). Patients with a CK-BB concentration of more than 50 ng/ml died. Patients, who had a CK-BB concentration less than 25 ng/ml showed only minimal neurological deficits. Intracerebral contusions and acute subdural haematomas showed the highest CK-BB concentration, indicating a high degree of braintissue-damage. CK-BB seems to have no correlation with the age of patients. Normalisation of elevated CK-BB levels do not correlate with recovery from neurological deficit.

Adolescent↗