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Biomedical subjects

R Bernard

Publications and source records attributed to R Bernard.

At least 145 records · Page 8Linked to original sources

[Amiodarone and thyroid function].

Amiodarone is a drug which is frequently used in cardiology, and which can lead to the appearance of hyper- of hypo-thyroidism in certain cases. A study of the various parameters of thyroid function has shown that these are abnormal in every case treated by this drug, without the biochemical abnormalities necessarily being reflected clinically. The authors outline a method which will allow a distinction to be drawn between patients with a true thyroid malfunction and those whose biochemical results do not appear at first sight to be of any consequence. Regular assays of the T3RIA level are suggested as a means of early detection of thyroid malfunction in patients undergoing treatment with amiodarone.

Amiodarone↗

[Trisomy 4p. Three new observations (author's transl)].

Three new observations of trisomy 4p are reported. Two are due to a maternal translocation t(4;15). The third is due to a "mirror" duplication, it is the first case of trisomy 4p without balanced parental rearrangement. The very characteristic phenotype is compared to that of 13 other patients already reported in the literature.

Abnormalities, Multiple↗

[Trisomy 8 in mosaicism].

Case report of a 6 year old girl without clear dysmorphism or mental deficiency. Chromosome studies, performed on blood lymphocytes, showed trisomy 8 in 80 % of the cells. This case is discussed with regards to a short literature analysis.

Child↗