[Fetal alcohol syndrome (author's transl)].
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Biomedical subjects
Publications and source records attributed to R Bernard.
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A woman presented a complex chromosome rearrangement with translocation between chromosome 2 and 4 in addition to an insertion of the band 4q12 leads to q13 in the long arm of chromosome 18. The authors present a case study of the daughter who displayed the abnormal chromosome 18 and trisomy of band 4q12 leads to q13.
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The need of admission of all patients with acute myocardial infarction in a CCU is questioned by some british authors. A critical review of their publications stresses the most important methodological problems they could not overcome; consequently they cannot allow any valuable comparison. There are no randomized trial related to the comparison of general ward to CCU care, but the available data obtained by studies based on bed availability show a definite advantage of the CCU. At the present stage of our knowledge, admission in a CCU must be recommended to all patients seen in the first hours after the presumed onset of the disease; after some delay (12 h?) systematic admission is not justified any more and the decision should be taken according to each case, in relation to the clinical status and familial or social conditions.
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37 children presenting with West's syndrome were studied by computerized tomography scanning. An abnormality consisting of diffuse cerebral atrophy, predominating in the fronto-temporal region, was demonstrated in 30 cases. The abnormality was sometimes associated with calcification (tuberous sclerosis) or malformation (agenesis of the corpus callosum). The aetiology of the atrophy and its relationship to clinical and electroencephalographic signs is discussed. Computerized tomography scanning is recommended for children with West's syndrome in order to distinguish between primary and secondary cases, and for greater prognostic accuracy.
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