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Biomedical subjects

P Winter

Publications and source records attributed to P Winter.

At least 109 records · Page 6Linked to original sources

Microbial methane oxidation in the River Saar.

In the River Saar, the distribution of methane-oxidizing bacteria and their metabolic activity were determined in vertical and longitudinal profiles. At the sediment surface about two orders of magnitude more methane oxidizers were detected than in the overlying water. In the river as well as in laboratory experiments, the rate of methane oxidation was closely related to the concentration of methane. Most of the methane produced by methanogenic bacteria in the the sediment escaped into the atmosphere. On the average only 1.2% of the produced methane was oxidized in the water phase.

Fresh Water↗

Acute and chronic effects of intrathecal morphine in monkeys.

In a double-blind study, seven Macaca fascicularis monkeys receiving intrathecal (i.t.) morphine in saline, 0.07 mg kg-1, were compared with a control group of four monkeys receiving either lumbar puncture alone (n = 1) or i.t. saline (n = 3). Neither morphine nor saline solutions contained preservatives. Arterial blood gas tensions, respiration, arterial pressure, e.c.g., state of consciousness and motor function were recorded for 24 h. The control group was sacrificed 42 days later and the study group was sacrificed at 6 (n = 2) or 42 days (n = 5) after injection. The central nervous system, meninges, nerve roots and dorsal root ganglia were examined macroscopically and microscopically. Respiratory depression did not occur in either the control or the study groups. There were moderate but statistically significant decreases in systolic and diastolic arterial pressures following i.t. morphine. In both groups, the pathological findings were localized to the cauda equina region and characterized by mononuclear cell infiltration. In neither group was there evidence of demyelination, arachnoiditis or necrosis. Focal endoneurial fibrosis was found in only one animal in the control group following multiple lumbar punctures associated with paraesthesia. The features appeared to correlate with the physical trauma associated with lumbar puncture rather than with the injectate.

Animals↗

Performance evaluation: continuous lumbar epidural anesthesia skill test.

The evaluation of skills in anesthesiology residents is usually subjective and lacks demonstrable reliability. Therefore, an objective criterion-referenced skill test for measuring performance of continuous lumbar epidural anesthesia was developed. For such a test to be useful, it is necessary to demonstrate agreement among rater-observers. Eight performances of continuous lumbar epidural anesthesia were recorded on video tape and simultaneously rated by nine anesthesiology faculty observers to determine inter-rater reliability. Inter-rater agreement was analyzed by determining coefficient kappa for each item and the entire test. Coefficient kappa for the entire test was 0.82 indicating a high degree of agreement between raters on the performance or nonperformance of various items. Development and utility of skill tests are discussed.

Anesthesia, Epidural↗

Echinococcosis in cattle and goats.

In the 500 cattles examined, 90 (18%) had hydatid cysts in one or more organs whereas only 12(2.4%) goats, out of 500 had the disease. This is considered to be due to shorter period of longevity and age of slaughter of goats compared to catte. Since dog is an important definitive host responsible for the spread of echinococcosis, a survey on the incidence of hydatid cyst in dogs is necessary from public health point of view.

Adult↗