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Biomedical subjects

P Stark

Publications and source records attributed to P Stark.

At least 145 records · Page 8Linked to original sources
PubMed1985

Thoracic radiographic changes after systemic hyperthermia for advanced cancer.

Systemic hyperthermia is an adjuvant method of treatment used in the management of advanced cancer; the hyperthermic state is induced by either the thermal blanket or the external blood shunt method. Strict monitoring of the cardiopulmonary status, the temperature, and the fluid balance is necessary. Chest radiographs were reviewed of 61 patients undergoing hyperthermia; pre-, intra-, and posthyperthermia radiographs were compared and significant radiographic findings tabulated. Intra- and postprocedural pulmonary edema, cardiomegaly, and pleural effusions were found in a significant number of patients. The radiologist should be familiar with systemic hyperthermia as a treatment modality for metastatic cancer and with the chest radiographic alterations resulting from it.

Adult↗
PubMed1985

Pseudolesion of the chest. A conglomerate shadow on the lateral radiograph.

A pseudolesion encountered in the lateral chest roentgenogram of normal patients is described. This concatenation of shadows can produce an opacity which projects over the distal aortic arch and can simulate a mass or pneumonia. This pseudolesion can be found in 4 to 5 percent of normal lateral chest films and is formed by superimposition of normal upper lobe vascular structures.

Diagnosis, Differential↗
PubMed1985

Tilted air-fluid interfaces on chest radiographs.

Three patients had hydropneumothoraces in which the air-fluid interfaces were tilted from the horizontal. One was examined fluoroscopically, and the interface "seesawed" synchronously with the heartbeat. Displacement of the fluid by cardiac pulsation is the most likely usual cause of tilted air-fluid interfaces in the chest.

Air↗
PubMed1985

Supplementary tissue-core histology from fine-needle transthoracic aspiration biopsy.

Biopsies of 150 consecutive suspected lung cancers were performed with fine needles having circumferentially beveled tips that produced cytology and tiny tissue cores suitable for histology. Visible tissue cores were aspirated in 92% (n = 138) and histologic diagnoses were obtained in 72% (n = 108). There were 118 (79%) proven malignant and 27 (18%) proven benign lesions. Sensitivity and specificity of cancer diagnoses were 97% and 100%, respectively. Biopsy histology was the only positive cancer specimen in two biopsies (1.7%). Biopsy cytology was the only positive cancer specimen in 20 cases (17.2%). Biopsy cytology and histology agreed with the proven cell type in 71.8% and 78.6% of cancers, respectively. As expected, when large-cell undifferentiated carcinoma was regarded as a nonspecific cell type consistent with either poorly differentiated adenocarcinoma or poorly differentiated epidermoid carcinoma, biopsy-cell-type accuracy increased greatly. Specific benign diagnoses were obtained in 44% of the 27 biopsies of proven benign lesions: cytology (four), core histology (five), and bacteriology (nine). Simple and complicated pneumothorax occurred in 10% and 4% of biopsies, respectively. It was concluded that biopsy with fine, circumferentially beveled needles can produce useful histology to supplement biopsy cytology.

Adenocarcinoma↗
PubMed1985

Lung cancer and pregnancy.

Two pregnant patients presenting with bronchogenic carcinoma are described. A retrospective study of patients with bronchogenic carcinoma as well as a review of the literature attest to the rarity of this combination. If current smoking patterns continue, the association of pregnancy and bronchogenic carcinoma will increase in frequency.

Adult↗
PubMed1985

Intrathoracic manifestations of sickle cell disease.

A retrospective analysis of 50 patients with sickle cell disease was performed. The majority of patients was admitted because of sickle cell crisis, pneumonia or congestive heart failure. Global cardiomegaly, pulmonary vascular engorgement, pneumonia and infiltrative lung parenchymal abnormalities were encountered. Our study shows a very high prevalence of intrathoracic abnormalities in patients afflicted with sickle cell disease.

Adolescent↗
PubMed1985

The pharmacologic profile of fluoxetine.

Fluoxetine is a selective inhibitor of serotonin uptake in vitro. Unlike many antidepressant drugs, fluoxetine has little affinity for muscarinic, histaminic H1, serotonergic 5-HT1 or 5-HT2, or noradrenergic alpha 1 or alpha 2 receptors on rat brain membranes in vitro. Fluoxetine inhibits serotonin uptake in vivo without affecting norepinephrine uptake. Neuroendocrine and behavioral consequences of enhanced serotonergic function resulting from fluoxetine's inhibition of serotonin uptake in vivo are described. Fluoxetine is relatively nontoxic in several animal species. The specificity of action of fluoxetine makes it a good candidate as an antidepressant drug.

Aggression↗
PubMed1985

[Esophageal rupture as a complication of the use of a Sengstaken-Blakemore tube].

We are describing a complication of the usage of Sengstaken-Blakemore tubes. Premature inflation of the gastric balloon in the esophagus can lead to rupture of the esophagus. This hazard can be avoided by checking the position of the tube with a chest radiograph before attempting to inflate the tamponading balloons.

Esophageal and Gastric Varices↗
PubMed1985

A review of multicenter controlled studies of fluoxetine vs. imipramine and placebo in outpatients with major depressive disorder.

The efficacy of fluoxetine was evaluated in depressed patients in double-blind imipramine- and placebo-controlled clinical trials. Fluoxetine produced greater improvement than placebo on all major efficacy parameters and was comparable to imipramine with respect to the primary indicators of depression. Fluoxetine had significantly less associated anticholinergic effects, dizziness, drowsiness, somatosensory disturbance, and excessive sweating than imipramine. Although nausea occurred more frequently in fluoxetine patients, it was generally mild and well tolerated. A significantly smaller percentage of fluoxetine than imipramine patients terminated therapy because of adverse experiences.

Adolescent↗
PubMed1984

Peripheral right upper lobe collapse in the newborn.

Three forms of peripheral right upper lobe collapse are described. One form has a straight or slightly concave medial border that mimicks pleural fluid. A second variety protrudes from the inferior lateral aspects of the atelectatic right upper lobe producing a triangular opacity that tapers inferiorly toward the chest wall. A third variety produces a convex medial interface with the lung that simulates an extrapleural mass or loculated fluid.

Diagnosis, Differential↗
PubMed1984

Traumatic rupture of the thoracic aorta: a review.

The frequency of traumatic injuries to the thoracic aorta has increased in recent years, paralleling the upward trend in the number of vehicular accidents. Blunt trauma is the predominant mechanism. In dealing with the survivors of the immediate impact, a high index of suspicion for aortic tears will allow the radiologist to recognize important signs on the chest roentgenogram; he will be able to direct further necessary steps and secure the diagnosis of an aortic tear. The following article will review the pertinent recent literature on the subject and emphasize a practical approach to the diagnosis of this not uncommon but life-threatening lesion.

Accidents, Traffic↗