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Biomedical subjects

P Sole

Publications and source records attributed to P Sole.

At least 37 records · Page 2Linked to original sources
PubMed1979

[Photochemistry of visual pigments (author's transl)].

Recent studies of the photochemistry of visual pigments are reported. Results obtained on rhodopsine and model compounds, by means of techniques based upon continous or pulsed excitation are compared. The mechanique of the primary photochemical step of the bleaching of rhodopsine is discussed. The process is occuring on a time scale of picosecond and a new concept of proton transfer followed by a conformation charge is opposed to the classical cis-trans photo isomerisation of the retinal moiety. The origin of the electrical response of the photoreceptor cells is still controversial.

Animals↗
PubMed1978

[Results of a double-blind study comparing the effects of timolol and pilocarpine in 110 patients with chronic open-angle glaucoma].

Following a seventeen weeks study including 110 patients with open-angle glaucoma, 81,8% of the patients treated by timolol, administered twice a day, had a satisfactory control of their intraocular pressure, against only 41,8% of those patients treated by pilocarpine, administered four times a day. The side effects liable to timolol are clinically reduced, in a osit with pilocarpine which is followed by a series of well-known subjective and objective signs often causing discomfort to the patients.

Aged↗