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Biomedical subjects

P Roux

Publications and source records attributed to P Roux.

At least 145 records · Page 8Linked to original sources

[Protein mapping of normal circulating cells: lymphocytes and monocytes].

Purified lymphocyte and monocyte populations were obtained from peripheral blood cells by ficoll-hypaque gradient and elutriation in different normal individuals. The two types of mononuclear cells were then analyzed by 2-dimensional gel electrophoresis. More than 1,000 spots were detected by our computer system and analyzed for each cell type. Automatic picture comparison showed a typical pattern for the two different populations with excellent reproducibility.

Blood Protein Electrophoresis↗

[Pneumothorax after ventriculoperitoneal shunt procedure].

A respiratory distress syndrome is reported in a four month old girl, after placement of a ventriculo-peritoneal shunt for hydrocephalus. This complication was related to a surgical pneumothorax. It was an early and spontaneously resolving complication, which one should have in mind after shunting procedures.

Cerebrospinal Fluid Shunts↗

Tongue and tonsil cancer: staging with US.

A prospective study on the value of ultrasound (US) for the staging of 70 cases of cancer of the tongue and tonsil was performed. A real-time, high-frequency transducer was used, and the examination was often coupled with endobuccal palpation. US did not visualize the tumor in nine of 42 cases of tongue cancer (seven stage T1 and two anterior stage T2 tumors); US accurately defined tumor size in 33 cases. The degree of in-depth extension and the location with respect to the median line (only four false results) were evaluated correctly. With regard to 28 tonsil cancers, US depicted extension from the tonsillar fossa to the tongue in all cases but one (13 of 14 cases). US is valuable for the detection of cervical lymph nodes associated with both tongue and tonsil tumors and is a safe and helpful technique for the follow-up of medium-size lesions. The major limitations of US include the nonvisualization of superficial lesions, reduced accuracy for evaluation of the extension of large tumors, and analysis of posterior pharyngeal extension.

Humans↗

Value of ultrasound in localizing the internal mammary vessels.

The authors discuss the value of ultrasound in determining the depth of the internal mammary vessels und their distance from the medial line. Real-time imaging with a high frequency transducer and a pulsed Doppler system gave highly accurate results. Depending on the intercostal space, the depth of internal mammary vessels varies from 17 to 22 mm. The distance of the internal mammary vessels from the medial line is a function of the intercostal space and the body side, and varies from 25 to 33 mm. Results were found to vary as a function of patient height and weight; likewise, mastectomy was seen responsible for a modification of 2 mm in measurements. Precise localization of the internal mammary vessels allows optimization of radiotherapy, and this rapid examination should be performed just prior to the start of irradiation.

Breast↗

CT and US findings in pancreatic ductal tumours. A report of an unusual case and review of the literature.

Pancreatic cystadenomas and cystadenocarcinomas are rare tumours usually occurring in women. The first symptoms are pain, occasionally associated with a palpable tumour in the left upper quadrant, and in rare cases the clinical and laboratory findings are suggestive of a pseudocyst. US shows a cystic neoplasm with a wall enclosing several polypoid areas. CT allows the diagnosis of the type of septa within the cyst and shows the extension of the lesion and calcifications into the wall. It also permits the assessment of the probable pathological complications associated with the tumour; therefore CT cannot differentiate cystadenoma from cystadenocarcinoma. The analysis of these different phenomena is based on one observation and a review of the literature.

Cystadenocarcinoma↗

Comparison of ultrasonographic and histological findings for multinodular lesions of the salivary glands.

Fifteen cases of multinodular lesions of the salivary glands are presented. All nodules were hypoechoic, the largest measuring over 5 mm. The various etiologies represented included: 8 non-Hodgkin's lymphomas, 5 metastases of cancer of the tongue, 1 sarcoidosis limited to the submaxillary gland, and 1 case of oncocytosis involving all four salivary glands. After discussing the rarity and the general characteristics of these lesions, the authors propose a diagnostic strategy following examination by ultrasound.

Adenoma↗

Ear, nose, and throat cancer: ultrasound diagnosis of metastasis to cervical lymph nodes.

We present the results of a study on the value of ultrasound in the detection of metastasis to the cervical lymph nodes in connection with cancer of the ear, nose, and throat. Comparison of clinical, ultrasound, and histological findings for 100 patients who underwent surgery revealed that clinical examination had a sensitivity of 78% versus 92.6% for ultrasound. All 18 cases of thrombosis of the internal jugular vein were detected by ultrasound. Clinical staging of the disease was modified in 28 of these patients based on ultrasound findings, including three false positive findings. Ultrasonographic follow-up at three months for a second group of 110 patients who did not undergo neck dissection provided prognostic information, since lesion stability or progression was correlated with death in less than one year in 41 of 43 patients. Ultrasound is of primary value in providing information of an anatomic nature, including the detection of subclinical lymph nodes, volumetric evaluation, and determination of vascular connections, particularly detection of internal jugular venous thrombosis. Furthermore, for patients whose necks have been thickened as a result of radiotherapy, ultrasound allows assessment of local status.

Antineoplastic Agents↗

Indications for ultrasonography in parotid pathologies.

In connection with 141 cases of parotid tumours, 21 adenopathies of the parotid region and 22 cases of parotitis, the authors define the role of ultrasonography in the exploration of the salivary glands. Use of simple criteria permits differentiation of benign from malignant tumours with a good degree of sensitivity (79.8% in our series). This score allows ultrasonography to be offered as the first complementary examination when dealing with a tumefaction of the parotid region. When ultrasonographic findings evoke a malignant lesion, a CT scan seems necessary to evaluate any extension in depth. In contrast, ultrasonography does not appear justified in cases of parotitis or lithiasic pathologies.

Diagnosis, Differential↗

Neurogenic tumors of the stomach. Report of 18 cases and review of the literature.

The general and radiologic features of neurogenic tumors of the stomach are reviewed in connection with 18 cases (16 benign and 2 malignant tumors). Such neurogenic tumors are rare in the stomach, representing less than 0.5% of all tumors. Solitary neurogenic tumors must be differentiated from those encountered during von Recklinghausen's disease. Radiological or endoscopic examination can generally determine the benign or malignant nature of solitary neurogenic tumors, which are essentially represented by schwannomas. Since these tumors are submucosal, a deep biopsy is imperative; furthermore, since such tumors are subject to hemorrhage, prior investigation by CT appears advisable to detect possible hypervascularization after injection of contrast material. For patients with von Recklinghausen's disease, a neurofibroma is usually diagnosed when faced with a digestive hemorrhage. Radiological exploration of the entire digestive tract appears essential to confirm the solitary nature of the gastric lesion and to be sure it is responsible for the clinical symptoms.

Adult↗

Ultrasonography of hepatic cavernous haemangiomas.

Cavernous haemangiomas, the most frequent benign tumours of the liver, are discussed by the authors in connection with 50 personal cases and surveillance of 35 solitary hyperechoic nodules less than 3 cm diam. without clinical or biological abnormalities. All the diagnostic images are reviewed but attention is focussed on ultrasound. All US patterns may be observed, but if the lesion is less than 3 cm, the echostructure is often hyperechoic and homogeneous. In view of their asymptomatic nature and the absence of risk of evolution for these small hyperechoic lesions, it appears legitimate to propose surveillance merely by US if there are no clinical symptoms and if liver function tests are normal.

Angiography↗

[Adenocarcinoma of the small intestine. Current state of diagnosis and treatment. A study of 27 cases and a review of the literature].

On the basis of 27 personal cases of adenocarcinoma of the intestine and a review of the literature, the authors discuss present-day knowledge about this pathology from both radiologic and therapeutic viewpoints. This study, which excludes papillary tumors, reveals that, on a para-clinical level, barium follow-through examinations allow correct diagnosis in 85% of cases. Arteriography does not provide any special data, and more recent techniques such as ultrasound and C.T. do not appear suited for use in initial investigations. From a therapeutic standpoint, surgery is the only effective solution, but long-term survival had not increased for forty years. This rare form of cancer, with an especially insidious clinical course, has thus not benefited from recently introduced diagnostic and therapeutic technics.

Adenocarcinoma↗