[Endorphins and the maternofetal entity].
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Amniotic Fluid↗
Biomedical subjects
P Riss
Publications and source records attributed to P Riss.
[Plastic surgery in prolapse and incontinence].
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Age Factors↗
[Reanastomosis of the rabbit fallopian tube with fibrinogen concentrate].
In order to investigate the use of fibrin glue in reconstructive surgery of the oviduct, tubal reanastomosis was performed with homologous fibrinogen concentrate in 26 rabbits. The contralateral tube was clamped. The pregnancy rate was 25%. No adhesions were seen in the area of the anastomosis on examination of the abdomen 3 months after operation.
Animals↗
[Long-term results of neural therapy in irritable bladder].
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Adult↗
Morphology of rabbit oviduct after reanastomosis with fibrin glue.
We examined the site of experimental reanastomosis with fibrin glue in rabbit oviducts 3 months after the operation with light and scanning electron microscopy. Local tissue reaction was minimal, no fibrin clots were seen and inflammatory reactions were almost absent. On scanning electron microscopy ciliated cells were reduced in number. Morphologic changes at the site of anastomosis after the use of fibrin glue appear comparable to the alterations seen after the use of microsutures.
Animals↗
[Vecchietti's operation for the formation of a neovagina: technic and results].
We performed Vecchietti's operation in 10 patients with absence of the vagina (8 Rokitansky-Küster-syndrome, 1 testicular feminization, 1 occlusion of the vagina after radiotherapy). There were no intra- or postoperative complications; on discharge the neovagina was patent for 2 fingers in all cases. On follow-up examinations 2 to 20 months postoperatively the neovagina was no longer patent in the patient after radiotherapy, all other patients had neovaginas with a length ranging from 5 to 9 cm and reported satisfactory coitus without dyspareunia. According to our experience the conditions for successful surgical formation of a neovagina are: good psychosocial adjustment, some preoperative sexual experience, higher age, preoperative counselling, and longterm follow-up.
Adolescent↗
[Onset and significance of postoperative bacteriuria].
In 52 patients an indwelling transurethral catheter was inserted after gynaecological surgery for 5 days; no patient received antibiotics. At the time of removal of the catheter on the 6th postoperative day and 2 days later (8th postoperative day) a urine culture was set up. At the time of removal of the catheter on the 6th day, 26/52 patients (50%) had significant bacteriuria greater than or equal to 10(5)/ml. In 11 out of the 26 patients with bacteriuria the urine cleared spontaneously within 2 days; on the other hand, 10/26 patients with a negative culture at the time of removal of the catheter had significant bacteriuria 2 days later. As a group these women also had delayed spontaneous onset of voiding and persistence of residual urine. Younger patients (less than 45 years) had significantly fewer bacteriurias on the 6th day than older patients. A positive urine culture at the time of removal of the catheter should be treated with antibiotics; a negative urine culture should be repeated whenever spontaneous voiding is delayed, when there is persistent residual urine, or when the clinical signs of urinary tract infection are present.
Adult↗
[Role of endorphins in the function of the lower urinary tract].
In order to investigate the influence of the endorphins on lower urinary tract function we antagonized the endogenous opiates with naloxone. We performed urodynamic examination in 17 incontinent women, administered intravenously 0.4 mg naloxone, and repeated the urodynamic examination. Bladder volume and pressure were not influenced by naloxone; the maximum urethral pressure showed a slight and urethral closure pressure a significant rise after naloxone treatment. Contrary to other authors, our results do not support a role of endorphins in lower urinary tract function.
Adult↗
[Clinical aspects and physiopathology of fetal left heart hypoplasia. 2 case reports].
2 cases of congenital hypoplastic left heart syndrome are presented with regard to clinical signs and pathophysiology. The hypoplastic left heart syndrome consists of a hypoplastic left ventricle and absence or atresia of the aortic valve, associated with severe hypoplasia of the ascending aorta and various degrees of mitral valve hypoplasia. Infants are well developed at birth but are unable to maintain sufficient circulation after physiologic closure of the ductus arteriosus.
Aorta, Thoracic↗
Evaluation and correlation of hormone levels in normal and pathologic pregnancies.
Estriol determination for monitoring high-risk pregnancies, either in serum or urine samples, has been in use for many years. The disadvantages are the inaccuracy of a 24-hour urine sample and the delay of two days. The advantages are a possible high variation of serum hormone evaluations from a very short sampling period. In order to prove the reliability of serum hormone patterns in pathological pregnancies, we compared them to 24-hours urinary E3 patterns. Free E3 and HCS levels were determined in serum samples by Radioimmunoassays. Total 24-hour urinary E3 was determined by a procedure according to Frandsen. For the graphic presentation, hormone levels from each pregnancy were grouped weekly and the mean values +/- SD in the different weeks of gestation were computed. To estimate the tendency of hormone patterns we performed a Z-transformation of grouped single hormone evaluations. A comparison between the serum and urine E3 measurements showed similar hormone patterns. E3 hormone patterns measured either in urine or serum proved to be well comparable. The mean of the transformed values showed the tendency of the hormone patterns even more distinctly than the graphic presentation. The hormone parameters E3 and HCS for monitoring high-risk pregnancies should be rated according to the diseases. In cases of placental insufficiency, E3 seemed to be the more sensitive parameter, whereas in severe cases of EPH-gestosis HCS might be more reliable.
Diabetes Complications↗
[Severe changes in the fundus oculi in pregnancy toxemia. 3 cases].
Three cases of severe retinal changes in conjunction with EPH gestosis are presented. 2 patients showed 4th degree hypertensive fundus changes (Keith-Wagener classification) and one suffered from bilateral exudative retinal detachment after an eclamptic fit in the 32nd week of pregnancy. The possible causes of retinal changes and visual disturbances in EPH gestosis are reviewed.
Adult↗
[Prostacyclin therapy in EPH gestosis (preliminary report)].
EPH-gestosis is still today one of the most dangerous complications of pregnancy, threatening both, maternal and fetal life. Until now only symptomatic treatment was possible. A new mode of treatment of EPH-gestosis may evolve from the use of prostacyclin, a potent vasodilator and inhibitor of platelet aggregation. We tried prostacyclin therapy in three patients with severe gestosis. The results of prostacyclin infusion on this condition, the pregnancy, the fetus, the placenta and the morphology of the umbilical artery are discussed.
Adult↗
[Clinical aspects and treatment of calf muscle cramps during pregnancy].
Of 8204 gravidae, 486 (5,9%) complained at least once of muscle cramps during pregnancy. Muscle cramps were noticed most often in the second half of pregnancy. Gravidae with muscle cramps were on the average older and of higher parity; there was no relationship between muscle cramps and complications during pregnancy or unfavorable fetal outcome. In an uncontrolled therapeutic trial 21 women with muscle cramps received 1,8 g monomagnesium-aspartate twice daily per mouth for 4 weeks. 21 women with muscle cramps had no therapy. 4 weeks after the initiation of magnesium therapy 19/21 women were free of symptoms, compared to only 7/21 patients in the control group. Muscle cramps during pregnancy do not have to be considered a risk factor; they can be significantly improved by the administration of oral magnesium.
Adult↗
[Detection and clinical significance of free circulating IgG immune complexes in EPH (edema, proteinuria, hypertension) gestosis].
With enzyme linked immunosorbent assays, using a solid phase Clq method, we determined free circulating immunocomplexes (CIC) in the serum of 47 pregnant women. In 30 normal pregnant women without EPH gestosis no CIC could be found. 3 normal pregnant women showed temporary CIC after viral infections. In 7 women with slight gestosis no traceable CIC concentrations were present. All 7 patients with medium or severe gestosis had clearly positive CIC levels simultaneous with hypertension and during the further course of the pregnancy. Hospitalisation and antihypertensive therapy had to be carried out because of increasing symptoms of gestosis. Thus only in medium and severe gestoses clearly demonstrable CIC concentrations could be measured. The presence of free circulating CIC might be a prognostically unfavourable indication for the further course of an EPH gestosis.
Adult↗
[Incidence and significance of fundus changes in EPH gestosis].
The authors examined 100 unselected pregnant women with EPH gestosis of different severity using the Keith-Wagener classification. In 52 women no fundus changes were observed; first-degree changes were seen in 32 women and second-degree changes in 10. Six gravidae presented with third or fourth-degree fundus changes. The average gestosis index was almost identical in the group without fundus changes and in the groups with first and second-degree hypertensive retinal changes, but significantly higher in the group with severe fundus changes (third or fourth degree). There was a clear correlation between the hypertensive fundus changes and blood pressure at the time of examination, in particular with regard to systolic blood pressure. An apparently normal fundus did not exclude the presence of a severe EPH gestosis; on the other hand severe retinal changes were sometimes seen in women with only mild EPH gestosis. Examination of the fundus in patients with EPH gestosis permits an objective assessment of vascular changes and provides a basis for further obstetric management.
Adult↗
[Coitus during pregnancy, vaginal flora and fetal outcome].
We studied a total of 105 women in late pregnancy in intervals of 2 to 4 weeks. At each prenatal visit we asked about the frequency of coital activity during the last 2 weeks, and took a vaginal smear for gram-staining. The frequency of coitus decreased with advancing gestational age. After 35 weeks, 42% of gravidae still reported coitus, one fourth of them with a frequency of more than 2 times per week. Purulent vaginal discharge and candidiasis were seen more often in women with frequent coital activity. There was no relationship between the frequency of coitus after 30 weeks and onset of labor or premature rupture of the membranes and fetal outcome (meconium staining, Apgar score, umbilical artery blood pH). Our study shows that a large percentage of pregnant women are sexually active near term. A negative influence of coital activity in late pregnancy on delivery and fetal outcome is not to be expected.
Adolescent↗
[Bladder dysfunction in pregnancy (author's transl)].
105 primiparous and 125 multiparous women have been asked for complaints of incontinence during their pregnancies. Multiparae suffered more often from stress incontinence, nullips reported a higher rate of urgency. The reasons and the influence of episiotomy, operative deliveries (forceps and vacuum) and pelvic floor training on incidence and recurrency of urinary incontinence during pregnancy are discussed.
Adult↗
[Urodynamic evaluation of the effect of neural therapy in motor and sensory urgency].
We treated 10 patients with motor or sensory urgency by paraurethral injection of a local anesthetic. After clinical and urodynamic work-up we applied 2.5 ml of 1% lidocain solution with Kollidon to delay absorption (Xyloneural) transvaginally to the right and left of the urethro-vesical junction. Each treatment cycle consisted of 3 injections with 2-week intervals between injections. 2 weeks after the last injection a repeat urodynamic investigation was done. All patients were improved by therapy: after the 3rd injection 3/10 women were free of symptoms, 6/10 women reported marked improvement, and one woman slight improvement of the symptoms of urgency and frequency. The mean bladder volume at the first sensation to void increased significantly after neural therapy (p = 0.02); other urodynamic parameters were not affected by neural therapy. No side effects were observed. We conclude that the paraurethral injection of a local anaesthetic is a simple and effective treatment in motor and sensory urgency.
Adult↗