Search PubMed⌕ Search

Biomedical subjects

P Petkov

Publications and source records attributed to P Petkov.

At least 91 records · Page 5Linked to original sources
PubMed1975

Electron microscopy of the endocrine pancreas of cattle (Bos taurus L.).

The electron-microscopic structure of the islets of Langerhans in cattle is studied. Four cell types are described: A, B, C and D, differing mainly in the structure of specific granules. In the A cells half-moon- or ring-shaped mitochondria are observed. Two modes of islet cell secretion are observed: by means of 'active-releasing sector's and emiocytosis.

Animals↗
PubMed1975

[Immunological reactivity of suckling pigs born to sows immunized against the lapinized K vaccine].

The lapinized K vaccine was used to immunize 25 five-day-old pigs and 27 ten-day-old pigs. A group of 10 pigs were also included in the experiment as controls. All animals originated from eight sows treated with a lapinized K vaccine on the 70th day of pregnancy. On the 14th day following vaccination part of the pigs of the two test groups were revaccinated. Three months later half of the immunized pigs were infected with a pathogenic swine fever virus. The remaining animals were infected then in a six months time following immunization. Systematic clinical and morphological investigations were carried out. It was concluded that the 5-day-old animals possessed much lower immunologic responsiveness to the lapinized K vaccine against swine fever as against the 10-day-old ones. Revaccination with the same vaccine on the 14th day led to a weaker immune response as compared to single vaccination. The immunity of the vaccinated 10-day-old pigs, originating from sows that had been immunized with the same vaccine during pregnancy, lasted about three months.

Age Factors↗
PubMed1975

Laser microprobe of cryostate sections of pancreas.

Laser microprobe was utilized in order to differentiate chemically the elementary composition of the A and B cells of Langerhans' islets and the exocrine parenchyma of the pancreas. An additional magnetic field was applyed to increase the sensitivity of the method.

Animals↗
PubMed1975

[Electronmicroscopic studies of the island of Langerhans of the rat pancreas after oral application of glibenclamide].

The morphological alterations of B-cells of pancreatic islets from rats were investigated 2, 8 and 24 h after a peroral application of glibenclamide. All cell organelles showed signs of activation, as enlargement of the rough endoplasmatic reticulum and the Golgi apparatus, increased number of mitochondriae and degranulation. These changes could be observed partly 2 h after glibenclamide, but the drastical alterations were found 24 h after application of the sulfonylurea.

Animals↗