Biomedical subjects
Publications and source records attributed to P Pavlica.
Osteosclerosis in the phalanges is a frequent finding in sarcoidosis and its incidence appears higher then that of the osteolytic lesions. Of 19 patients with histological diagnosis of sarcoidosis areas of bone sclerosis in the phalanges were found in 6 cases (31, 5 percent).
The systematic exploration of the skeleton on patients in periodic hemodialysis, has shown a high incidence in alteration of sacro-iliac junctions. In respect of osteodystrophic alteration of the phalanges, the appearance is late and with continued hemodialytic treatment there is a turn for the worse. The exact definition has been obtained only with tomography. The radiological picture show a pseudoenlargement of the articular cleft, with shaded aspect of outlines and phenomena of periarticular bone thickening.
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Retrograde urethrography is the method commonly employed in the detection of anterior male urethra pathology. Ultrasonography and magnetic resonance imaging have been proposed recently as new methods that can replace conventional radiography. Normal urethral anatomy can be easily studied after saline distention of the urethra, which creates high contrast relative to adjacent structures such as mucosa and corpus spongiosum. Sonourethrography with high-frequency probes has a high spatial resolution and has proved to be sensitive, specific, and accurate in the diagnosis of anterior urethral pathologies such as strictures, syringocele, tumors, and trauma. It has a major role in the selection of therapy in patients with bulbar strictures. Magnetic resonance imaging with a surface coil with a small field of view can detect penile and bulbar stenoses and tumor extension. After contrast administration, the activity of the inflammatory process in the spongiosum can be assessed and used to modify the urethroplasty technique. The clinical use of the new imaging modalities in the male anterior urethra is limited despite their demonstrated accuracy in diagnosis and presurgical staging of different diseases.
A 60-year-old man who had been suffering from psoriasis for 20 years developed finger dactylitis and inflammatory swelling with pitting edema over the dorsum of the hand one week after a contusive trauma to the left hand. These were not followed by any other clinical manifestations of PsA.
The cause of musculoskeletal symptoms in polymyalgia rheumatica (PMR) is not clearly defined because joint synovitis may only partially explain the diffuse discomfort. MRI imaging of the shoulders, hip and extremities of patients with PMR has been analyzed. MRI showed that subacromial and subdeltoid bursitis of the shoulders and iliopectineal bursitis and hip synovitis are the predominant and most frequently observed lesions in active PMR. The inflammation of the bursae associated with glenohumeral synovitis, bicipital tenosynovitis and hip synovitis may explain the diffuse discomfort and morning stiffness.