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Biomedical subjects

P Netter

Publications and source records attributed to P Netter.

At least 397 records · Page 22Linked to original sources
PubMedDate not supplied

Influence of sulfasalazine on established collagen arthritis in rats.

Collagen induced arthritis (CIA) in rats is an experimental model that is characterized by an erosive synovitis associated with periostitis and both peripheral and axial ossifying enthesopathy. The influence of long-term therapy with sulfasalazine (80 mg/day on weekdays) on established CIA in Wistar Furth rats was investigated. Clinical and X-ray examination showed a significant improvement in the joint lesions of the uninjected paws in the treated rats as compared to controls. This effect was, however, delayed. On the other hand, periosteal new bone formation and caudal enthesopathy (spondylodiscitis) were not altered by the treatment.

Animals↗
PubMedDate not supplied

[A 30-month study of the calls to the Regional Drug Monitoring Center in Lorraine (Nancy)].

For over a period of 30 months, all the questions to the French "Centre de Pharmacovigilance" of Nancy Lorraine have been analysed. The University Hospital of Nancy is by for the main caller (65%) and the suspicion of adverse drug reaction represents 61% of all the questions. Gastrointestinal and hepatic disorders, cardiovascular drugs arouse the greatest number of questions. Comparison with results previously published by some French Pharmacovigilance Centres points out some regional particularities.

France↗
PubMedDate not supplied

[Argyria].

Explore the source record for details and available documents.

Acute Disease↗
PubMedDate not supplied

[Determination of protein binding of drugs using equilibrium dialysis. Influence of volume displacement caused by osmotic pressure].

By the determination of the free concentration of a drug using the equilibrium dialysis method, a volume shift could be observed, inducing a dilution of the protein medium. The value of this volume shift varies with the plasmatic sample and could produce a misdetermination of the free fraction which could be important, essentially for the drugs strongly bound to proteins.

Blood Proteins↗