[Stimulation of Australia antigen production].
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Biomedical subjects
Publications and source records attributed to P Maupas.
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Several automatic methods have been described for complement-fixation tests. However, each of these methods presents some inconvenience either due to cross contamination or to limited sensitivity. The new method consists basically in separating clearly the fixation stage from the haemolytic stage by using two different sampler plates placed on the same sampler. By this procedure, it becomes possible to obtain a very high sensitivity. The serologist may set the temperature and the duration of the reaction according to the properties of the tests under study. In addition, the sampling rate can be raised to 120 analyses per hour.
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Sensitivity and specificity of anti-HBc detection by counter-immunoelectrophoresis (CEP), complement fixation (CF) and radioimmunoassay (RIA) tests were compared in sera from 69 patients with chronic hepatitis, 61 black African people suffering from primary hepatocellular carcinoma and 50 controls composed of French country people. CEP and CF tests gave the same results in detecting anti-HBc antibodies. The RIA test was found to be more sensitive and seems to be more specific than CEP and CF.