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Biomedical subjects

P Marks

Publications and source records attributed to P Marks.

112 records · Page 7Linked to original sources

The embryologic basis of tracheobroncho-pulmonary maldevelopment.

An integrated analysis of 15 patients with tracheobronchial abnormalities, bronchogenic cysts and pulmonary sequestration demonstrates that these diverse clinical conditions are expressions of basic embryologic maldevelopment patterns. The clinical conditions described are indicative of differences in degree of the embryologic disorder. In addition to the clinico-pathologic changes affecting the tracheobroncho-pulmonary components of the respiratory system, the importance of aberrant pulmonary arterial blood vessels is described and the diagnostic importance of ancillary investigations is emphasized.

Bronchi↗

The use of allograft bone in revision of total hip arthroplasty.

Fifty-two frozen bone allografts have been used on 44 patients undergoing revision hip arthroplasties. The average follow-up time on these patients has been 17 months, with a range of six to 72 months. Both proximal femoral allografts and the allografts for the reconstruction of acetabular deficiencies have been used. To date, most patients experience marked pain relief and improvement in function. Though the results attained to date are short-term, the use of allografts in the revision hip arthroplasties represents a natural progression of the tumor work. However, while the early results are encouraging, it remains to be seen how the proximal femur allografts and the large acetabular allografts will behave over a long period of time.

Acetabulum↗

Non-invasive mechanical ventilation: the benefits of the BiPAP system.

Many of the complications with endotracheal intubation and invasive mechanical ventilation can be avoided with the use of non-invasive mechanical ventilation (NIMV). This technique has been especially successful in treating patients with acute respiratory failure (ARF). NIMV improves gas exchange, avoids complications caused by endotracheal intubation, and allows patients to talk and take medications orally. This article reviews our experiences treating 27 patients with ARF with a BiPAP (bi-level positive airway pressure) ventilator. This is a portable unit which allows for selection of different modes of ventilation and adjustment of inspiratory and expiratory pressures. Non-invasive mechanical ventilation should be considered in patients presenting with ARF who are hemodynamically stable and in whom spontaneous breathing is preserved.

Case-Control Studies↗