Search PubMed⌕ Search

Biomedical subjects

P Litoux

Publications and source records attributed to P Litoux.

At least 91 records · Page 5Linked to original sources
PubMed1985

A study of intermediate filaments (cytokeratin, vimentin, neurofilament) in two cases of Merkel cell tumor.

In two cases of Merkel cell tumor, the study of intermediate filaments, using monoclonal antibodies (vimentin, cytokeratin, neurofilaments), confirmed the double differentiation (neuroendocrine and epithelial) of this tumor as previously observed in histological, electron microscopical and histochemical analyses. Labelling of the tumor cells was positive with monoclonal antibodies against neurofilament proteins and cytokeratin.

Adenocarcinoma↗
PubMed1984

[Value of correlated immunofluorescence and immunoperoxidase study of monoclonal markers in 2 adult cases of histiocytosis X].

Two cases of adult histiocytosis X have been studied using monoclonal antibodies on skin sections by two techniques: indirect immunofluorescence and immunoperoxidase. This study confirm: --that histiocytosis X express two specific antigens Ia and T6, --the relations between Langerhans cell and histiocytosis X. Especially, it suggests that histiocytosis X cell would be a dedifferentiated cell with receptors OKT4 and OKT10.

Adult↗
PubMed1984

[Flaps in the reconstructive surgery of dermatologic epitheliomas of the nose (excluding rhinopoiesis). Apropos of 144 surgically treated cases].

Dermatologic epithelioma of the nose is usually a basocellular and more rarely a spinocellular epithelioma. Small tumors less than 5 mm in diameter can be treated by electrocoagulation, whereas those over 1 cm should be treated by surgery or physical methods. Of a total of 144 cases of epithelioma operated upon, 10% were reconstructed by a flap. Increasing use is being made of local anesthesia with subsequent reduced hospital stay. The quality of the carcinologic results, similar to that of physical methods, and the excellent healing obtained, particularly in elderly patients, are arguments in favor of extensive surgery for epitheliomas in this region. The quality of the resection is difficult to evaluate, unless results of a fresh specimen examination are available. When not possible then it is preferable to await results of histology to show limits of excision before performing an autoplasty with flaps.

Basal Cell Carcinoma↗
PubMed1984

[Cutaneous achromia and malignant melanoma].

A cutaneous depigmentation occurring either far, or the primary tumour, or about the excision scar, or appearing in different other conditions was noted 29 times among 500 cases of malignant melanoma. Before excision, a vitiliginous depigmentation was present only in two patients. Nevertheless 9 patients observed a vitiligo after surgical excision of the tumour (2.5 years after, as an average) this proportion must conjecturally increase thereafter and so represent a minimal score. Twice, an achromic halo was obvious around the primary melanoma. In seven patients there was evidence of secondary depigmentation around the excision. Seven times a localized achromia was observed on the site of BCG-application or DNCB-test. Two patients had a halo-naevus (Sutton naevus). These varying achromias accompanying malignant melanoma were largely studied in animal pathology (horse and chimpanzee). They are usually in animals a factor of good prognosis. This good prognosis was likewise related in human malignant melanoma, but our series is against the assertion of any prognosis significance.

Female↗
PubMed1980

[Eczematoid dermo-epidermitis].

A methodic study of 50 cases, had to the discussion of a real clinical well established entity. The lesions start from an initial site, located on the inferior limbs in 2/3rd of the cases; then within a variable period of time extend larger and larger by proliferating in numerous patches. These lesions present as polymorphic, erythemato-squamous or oozing. They often evolve towards recurrence. The disease is more frequently encountered among 50-year-old men. Several factors contribute to the onset of the lesions: chronic alcoholism--lack of sanitary conditions--microbial background--stasis--overweight. A disturbed system of cutaneous protection and a lack of immune defences versus an antigen, probably a bacteria, are at the origin of the pathogenesis of these disorders. Considering the treatment, we wish to underline the benefit of local coal tar applications.

Adult↗
PubMed1979

[Pyoderma gangrenosum and haemopathy. Report of three cases (author's transl)].

The authors report three personal cases of phagedenic pyoderma associated with hemopathy. Studying twenty-five other cases, described in the reviews, the question can be debated on three levels: 1) The clinical characteristics of hemopathic pyoderma remain non-specific. However blisters, pustules, and even vegetating lesions occur very often; 2) the etiology of hemopathy is subject to change; acute leukaemia or myeloproliferation syndrome. During the polyglobulars associated with pyoderma, anemia and myelofibrosis appear quite constantly; 3) finally on the pathogenic level, the recent works tend towards the hypothesis of a damage in the functioning of the polymorphonuclears hence displaying the increase in the inflammation during phagedenic pyoderma.

Adolescent↗