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Biomedical subjects

P Leclercq

Publications and source records attributed to P Leclercq.

59 records · Page 4Linked to original sources
PubMedDate not supplied

[Clinical case of the month. Rendu-Osler-Weber disease: a rare case of stroke in the young].

Rendu-Osler disease or hereditary hemorragic telangiectasia is a group of autosomal dominant diseases characterized by angiodysplasic lesions in the skin, mucous membranes and viscera with risks of recurrent bleedings. Neurological complications have been described in 10-30% of these patients, most often hemorrhagic or septic. More exceptionally, ischemic strokes occur in these patients, particularly if they have pulmonary arteriovenous malformations. We report the observation of a 25 year old man who developed a latero-protuberantial stroke. The explorations revealed pulmonary AV malformations and nasal telangiectasias that led to the diagnostic of Rendu-Osler disease. This affection should be considered as a potential cause of cerebral ischemic attack, particularly in young patients without risk factors.

Adult↗
PubMedDate not supplied

[Burned patients center and hospital hygiene (author's transl)].

The author specifies that seriously burned patients, i.e. over 15% of body surface, should be treated in specialized centers given the hygiene problems they present. He describes the main principles that should guide the conception and realization of such a center stressing the isolation from the general hospital and technical aspects that prevent contamination of the areas and cross-infections of patients.

Asepsis↗
PubMedDate not supplied

[Health economics and antibiotic therapy].

In the field of antibiotic therapy, particularly the methods of economic evaluation hold one's attention within the wide range of health economics' applications. Several tools allow a comparison of the outcomes of alternative strategies and thereby guide choices to the most appropriate solutions. After a brief recall of the methods classically used to evaluate health care strategy, the authors stress the importance and difficulty of fixing and applying a correct and satisfactory procedure for evaluation. An evaluation example of antibiotic therapy allows to illustrate the application of the principles confronting a field in which competition is intense and economic stakes stay large--a fact which naturally yields to seek after objective decision making criteria. The health care policies drawn by public authorities as well as the marketing strategies of the health sector trade are partly based on such evaluations. If these techniques are not intended for the practitioner in the first place, they should not be indifferent to him since they influence health authorities and thereby indirectly affect the therapeutic freedom of the physician.

Anti-Bacterial Agents↗