Thin needle aspiration cytology of the breast.
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Biomedical subjects
Publications and source records attributed to P Ide.
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In one hundred patients treated by means of one gram medroxyprogesterone a week for disseminated or recurrent endometrial adenocarcinoma, vaginal cytohormonal evaluation seemed to be an important predictive factor of hormone dependency and tumoral responsiveness to progestational therapy. Almost all 51 patients, representing the responsive group, revealed an evident drop of the Karyopyknotic Index and a complete shift to the left of the Maturation Index. Both cytohormonal and tumoral response to medroxyprogesterone seemed directly related to estrogen-progestogen interaction on a cellular level. The striking LH response in the responsive group has previously not been integrated in this mechanism of action.
The comparison between clinical examination, mammography, thermography and fine needle aspiration cytology shows the usefulness of cytology in differential diagnosis of benign and malignant breast tumours. The cytology shows the real nature of benign suspicious and malignant mammographic and thermographic results. Specially in the younger patients cytology identifies early tissue changes, invisible on mammography. Application of the TNM classification shows TOT1 T2 tumours 72% of the material, with 90% positive cytologic results.