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Biomedical subjects

P Ide

Publications and source records attributed to P Ide.

At least 19 recordsLinked to original sources
PubMed1999

A successful practice model for the OR.

A practice model that combines shared governance and patient care teamwork to achieve optimal surgical patient care provided the framework for a successful Joint Commission on Accreditation of Healthcare Organizations visit at the Brigham and Women's Hospital, Boston, a university-affiliated teaching hospital. This article describes ways to implement this practice model. Clinical practice, quality improvement, and development councils are explained, as well as membership criteria for the councils and how they function. The need for more sharing of such quality improvement data from other hospitals is needed to establish national standards for measuring nursing performance.

Adult↗
PubMed1994

Primary lymphoma of the uterine cervix.

A case of primary non-Hodgkin lymphoma of the uterine cervix is reported. The ultrasonographic and computed tomographic findings are described as well as the MRI appearance of this peculiar cervical mass. The best tumor delineation was achieved by T2-predominant and contrast-enhanced T1-weighted images. The lesion was treated successfully with external radiotherapy.

Adult↗
PubMed1992

An unusual type of endometrial cancer, related to tamoxifen?

Tamoxifen, which is increasingly being used in breast cancer patients, has been associated with an elevated frequency of endometrial carcinoma. To our knowledge not a single case of uterine serous papillary carcinoma (USPC) has been documented during tamoxifen treatment. No conclusions as to a causal relationship are yet being made, but if it is due to tamoxifen, we should advise a strategy for prevention, because this subtype is not as curable as endometrioid carcinoma.

Cystadenocarcinoma↗
PubMed1992

Ovarian borderline mucinous tumor in a premenarchal girl: review on ovarian epithelial cancer in young girls.

Ovarian tumors constitute the most common gynecological neoplasms during childhood. Unlike in adult women, ovarian epithelial tumors are uncommon in young girls and extremely rare prior to menarche. To our knowledge this is the first report of a borderline malignant mucinous tumor of the ovary in a premenarchal girl. It was successfully treated by conservative surgery. In our review of ovarian neoplasms in girls under 20 years of age, epithelial tumors were found in 19.3%, with a malignancy rate of 15.9%. Of these malignant tumors, 39.4% were of the mucinous type and 30.3% were borderline malignant. The occurrence of such a tumor at this age underscores the possibility of malignant transformation of the ovarian epithelium even prior to menarche. Its mucinous nature confirms the predominance of the mucinous subgroup in young girls. Hypotheses on the origin of mucinous tumors are discussed.

Adolescent↗
PubMed1992

Operating room productivity. An evaluation format.

Operating room (OR) directors are frequently faced with the challenge of explaining or justifying OR productivity and the OR staffing budget. This justification may occur annually in conjunction with their budget submission or when consultants are employed to evaluate and improve OR productivity. Whatever the circumstance, a simple step-by-step format that helps physicians and administrators understand the impact of productivity on the nursing budget can be most useful. The authors present a format that was successfully used at a Boston teaching hospital.

Boston↗
PubMed1987

Computed tomography and lymphography in the presurgical staging of early carcinoma of the uterine cervix.

The value of bipedal lymphography and computed tomography (CT) in the presurgical staging of early carcinoma of the uterine cervix was analysed in 62 patients by histologic examination of pelvic lymph nodes and parametrial extension at the time of surgery. Macroscopic invasion of the lymph nodes was detected in 33% of the patients by CT and in 17% by lymphography. Microscopic invasion was suspected in 9% by CT scan and in 38% by lymphography. Physical examination with measurement of the tumor diameter was more predictive for regional extension of the disease as compared to lymphography and CT. CT may detect subclinical parametrial invasion but overestimation of the extent of the disease is common. Bipedal lymphography and CT add only limited information to the routine presurgical staging of cancer of the uterine cervix.

Adult↗
PubMed1986

Endometrial morphology during a normophasic and a triphasic regimen: a comparison.

It is expected that cycle control during oral contraceptive regimens may be correlated with the pattern of gradual endometrial maturation. Therefore the objective of the present study was to investigate the endometrial histology during a normophasic and a triphasic preparation. Biopsies were obtained at different intervals in the second treatment cycle from 21 women taking a triphasic pill and from 21 women taking a normophasic pill. The morphology of the endometria during the two regimens was evaluated and compared, as well as with the normal cycle histology. The study showed an early progestational effect and a rather hypoplastic growth during the triphasic regimen. The normophasic preparation was characterised by a better development and a more balanced glandular growth in proportion to the stroma, imitating the normal physiological mucosal changes very closely. From these observations it is concluded that a more reliable cycle control may be achieved by the use of this normophasic oral contraceptive as compared with the triphasic pill.

Adult↗
PubMed1986

Modalities and results of a combined anti-estrogenic therapy by means of tamoxifen and medroxyprogesterone in gynecologic cancerology.

In the therapeutic schemes of the hormone-dependent gynecologic cancers, the combined administration of tamoxifen and medroxyprogesterone, generally, scores better results. The highly hormone-dependent tumors (ER+, PgR+) respond very well to a combined, simultaneous treatment. The strictly hormone-dependent (ER+, PgR-) and the potentially hormone-dependent (ER-, PgR-) tumors seem to be most efficiently treated by means of a combined, successive scheme.

Adenocarcinoma↗
PubMed1984

Prognostic value of peritoneal fluid cytology in patients with endometrial cancer stage I.

With increasing depth of invasion of the endometrial adenocarcinoma in the myometrium an increasing number and percentage of patients with endometrial adenocarcinoma cells in the pouch of Douglas are found. The presence or absence of endometrial tumour cells can be used as an indicator of the depth of invasion in the myometrium. Survival is correlated with the presence of endometrial adenocarcinoma cells in cases with deep invasion; 50% recurrent disease was observed when the fluid was positive, no recurrent disease when negative. No correlation between survival and presence or absence of tumour cells in the Douglas fluid was found in cases with superficial invasion of the tumour in the myometrium.

Adenocarcinoma↗
PubMed1982

[Correlation between cell fluorescence for estrogen receptors and the hormone-dependence of breast cancer].

In 27 postmenopaused patients cellular ER has been assessed after fine needle aspiration by estimation of the cytoplasmic or nuclear fluorescence intensity after incubation with 27 beta-estradiol-6-carboxymethyl oxime-bovine serum albumin-fluorescin isothiocyanate. The cellular changes in the fluorescence intensity and tumor size after a 7 days treatment with Tamoxifen (TMX) have been studied. These factors have been correlated with the anatomoclinical factors. Three different groups of patients can be distinguished; in the first group of 10 patients with predominantly cytoplasmic ER fluorescence before treatment with TMX, tumor reduction and disappearance of the cytoplasmic ER fluorescence are observed in a group with the best anatomoclinical factors. In a second group of 7 patients moderate cytoplasmic and some nuclear ER fluorescence is observed. After the 7 days treatment with TMX tumor reduction is found in cases with diminished nuclear ER fluorescence, on the contrary an increase in nuclear ER fluorescence is found in fast growing tumors, with stationary tumor size after 7 days TMX treatment. A third group of 10 patients displays only nuclear ER fluorescence. After the 7 days treatment with TMX, no change occurred in tumor size, with increase of the nuclear ER fluorescence in 8 patients with fast growing tumors, in 2 patients the diminished nuclear fluorescence was accompanied by a decrease in tumor size.

Breast Neoplasms↗
PubMed1980

New aspects of the pathophysiology of endometriosis and associated infertility.

After ovulation, peritoneal fluid contains concentrations of progesterone and of 17 beta-estradiol that are 5 to 20 times higher than plasma concentrations in women with ovulatory cycles but not in women with unruptured luteinized follicles. Since viable endometrial cells were found in the peritoneal fluid of over 50% of women, both with and without endometriosis, a new hypothesis is presented about the etiology of pelvic endometriosis and the association of pelvic endometriosis and infertility: pelvic endometriosis could be the consequence of infertility caused by the unruptured luteinized follicle.

Ascitic Fluid↗