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Biomedical subjects

P Gane

Publications and source records attributed to P Gane.

102 records · Page 6Linked to original sources
PubMedDate not supplied

Phosphatidylserine exposure and aminophospholipid translocase activity in Rh-deficient erythrocytes.

Endogenous phosphatidylserine (PS) exposure and lipid transport activity have been investigated for seven unrelated cases of Rhnull erythrocytes. Endogenous PS exposure was measured by prothrombinase activity. Out of six cases studied, two Rhnull samples exhibited abnormal aminophospholipid exposure, as suggested by the measurement of a lower Km of factor Xa for prothrombin. Aminophospholipid translocase activity was measured through the transbilayer redistribution of spin-labelled analogues of phospholipids. Provided that incubation conditions allow the maintainance of intracellular ATP level, no difference was observed between Rhnull and control erythrocytes, clearly indicating that the aminophospholipid translocase and Rh polypeptides are different molecular species.

Adenosine Triphosphate↗
PubMedDate not supplied

[Rejection of discordant xenografts of the liver and heart].

Comparative study of the rejection of 26 heart and liver xenografts in strain discordant combination (guinea pig/rat lewis) allows the authors to establish the liver's weakest sensibility to natural xenoantibodies, the modesty of histological signs on liver xenograft rejection, and these lost's more longer survival. The results are compared to those obtained with 26 heart and liver isografts.

Animals↗